{"_buckets": {"deposit": "5eab2d35-8019-4a2f-96f0-dbd48d014a7e"}, "_deposit": {"id": "9098", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "9098"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00009098", "sets": ["501"]}, "author_link": ["25522", "25523", "25524", "25525"], "item_10_alternative_title_19": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Gene Therapy for Malignant Glioma", "subitem_alternative_title_language": "en"}]}, "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2006-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "704", "bibliographicPageStart": "700", "bibliographicVolumeNumber": "15", "bibliographic_titles": [{"bibliographic_title": "脳神経外科ジャーナル", "bibliographic_titleLang": "ja"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The merging of bio-technology, nano-technology, and computer technologies has led to the  creation of new advanced medical fields including gene therapy. In 2000, we started a  clinical trial of the first original gene therapy for malignant glioma based on made-in-Japan  technology, and confirmed the safety and effectiveness of this therapy. The results led to  the founding of the Center for Genetic and Regenerative Medicine (CGRM), which is an  institute to put advanced medicine into practice in our Nagoya University Hospital.  In 2006, CGRM gained ISO (International Organization for Standardization) 9001: 2000 and  13485: 2003 accreditation. We are now the first academic institute in Japan to achieve  ISO Certification. At CGRM we are making an effort to gain a better understanding of  advanced medical services with the goal of ensuring that our patients receive the best  available, safe and effective medical services. バイオテクノロジー,ナノテクノロジーやコンピュータテクノロジーは,遺伝子治療をはじめとする新しい先端医療を生み出してきた.われわれはその時代の中で,2000年に純国産技術で作り上げた最初の遺伝子治療を悪性クリオーマを対象に行い,その安全性および有効性を確認した.その成果は,名古屋大学医学部附属病院内に設置された先端医療開発施設,遺伝子・再生医療センターに引き継がれた.同センターでは,2006年,そこで作られる先端医療マテリアルの品質を保証するため,ISO9001(2000)および13485(2003)を取得した.この取得は,大学関連施設ではわが国初である.この施設での活動を通して,患者に役立つ新しい先端医療開発を進めていくことになっている.本稿では,われわれが行っている悪性クリオーマに対する遺伝子治療と,それに関連したわれわれの活動を紹介し,これからの先端医療のあり方について展望した.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "(\u003c特集\u003e悪性脳腫瘍の病態と治療) (\u003cSPECIAL ISSUE\u003ePathology and Treatment of Malignant Brain Tumors)", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/10865"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本脳神経外科コングレス", "subitem_publisher_language": "ja"}]}, "item_10_relation_43": {"attribute_name": "関連情報", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://ci.nii.ac.jp/naid/110004812441/", "subitem_relation_type_select": "URI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "日本脳神経外科コングレス", "subitem_rights_language": "ja"}, {"subitem_rights": "本文データは学協会の許諾に基づきCiNiiから複製したものである", "subitem_rights_language": "ja"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0917950X", "subitem_source_identifier_type": "PISSN"}]}, "item_10_text_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "水野, 正明", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "25522", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "吉田, 純", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "25523", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizuno, Masaaki  Masaaki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "25524", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshida, Jun", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "25525", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "mizuno_1215.pdf", "filesize": [{"value": "1.4 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 1400000.0, "url": {"label": "mizuno_1215.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/9098/files/mizuno_1215.pdf"}, "version_id": "04437adf-0c5b-42e0-8af4-50db0d13996c"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "malignant glioma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "gene therapy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "advanced medicine", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "悪性グリオーマに対する遺伝子治療", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "悪性グリオーマに対する遺伝子治療", "subitem_title_language": "ja"}]}, "item_type_id": "10", "owner": "1", "path": ["501"], "permalink_uri": "http://hdl.handle.net/2237/10865", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2009-01-22"}, "publish_date": "2009-01-22", "publish_status": "0", "recid": "9098", "relation": {}, "relation_version_is_last": true, "title": ["悪性グリオーマに対する遺伝子治療"], "weko_shared_id": -1}