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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 71(1-2)

MULTILEVEL ANALYSES OF EFFECTS OF VARIATION IN BODY MASS INDEX ON SERUM LIPID CONCENTRATIONS IN MIDDLE-AGED JAPANESE MEN

https://doi.org/10.18999/nagjms.71.1-2.19
https://doi.org/10.18999/nagjms.71.1-2.19
07d155fd-2b3f-4a20-a6d5-d2daace7c77f
名前 / ファイル ライセンス アクション
p019-028_Kondo.pdf p019-028_Kondo.pdf (74.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2009-03-16
タイトル
タイトル MULTILEVEL ANALYSES OF EFFECTS OF VARIATION IN BODY MASS INDEX ON SERUM LIPID CONCENTRATIONS IN MIDDLE-AGED JAPANESE MEN
著者 KONDO, TAKAAKI

× KONDO, TAKAAKI

WEKO 27541

KONDO, TAKAAKI

Search repository
KIMATA, AKIKO

× KIMATA, AKIKO

WEKO 27542

KIMATA, AKIKO

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YAMAMOTO, KANAMI

× YAMAMOTO, KANAMI

WEKO 27543

YAMAMOTO, KANAMI

Search repository
UEYAMA, SAYOKO

× UEYAMA, SAYOKO

WEKO 27544

UEYAMA, SAYOKO

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UEYAMA, JUN

× UEYAMA, JUN

WEKO 27545

UEYAMA, JUN

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YATSUYA, HIROSHI

× YATSUYA, HIROSHI

WEKO 27546

YATSUYA, HIROSHI

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TAMAKOSHI, KOJI

× TAMAKOSHI, KOJI

WEKO 27547

TAMAKOSHI, KOJI

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HORI, YOKO

× HORI, YOKO

WEKO 27548

HORI, YOKO

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キーワード
主題Scheme Other
主題 Multilevel analysis
キーワード
主題Scheme Other
主題 Random effect
キーワード
主題Scheme Other
主題 Serum lipid
キーワード
主題Scheme Other
主題 Weight variation
キーワード
主題Scheme Other
主題 Industrial health
抄録
内容記述 For the effective use of the annual workplace health checkup data, we tried to perform multilevel analyses to explore whether the year-to-year weight variation causes any concurrent effects on the lipid profiles among middle-aged Japanese workers. Subjects were 1,939 healthy male workers 40–59 in age from whom serial data of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) were collected during health checkups conducted in the years 1997–2000. The effects of body mass index (BMI) on serum concentrations of those lipids were investigated by statistical analysis with multilevel modeling to distinguish multiple levels of information with individual repeated measurements within individuals. A significant increase of TC and TG, and decrease of HDL-C with BMI increase were confirmed. Subanalyses according to both the baseline BMI status (< 25 kg/m_2 or ≥ 25 kg/m_2) and smoking status (never, former, or current) yielded the same BMI-dependent changes of lipid profiles, but obese never smokers failed to show significant effects of BMI on HDL-C concentrations. Multilevel analyses of annual health checkup data linked at individual levels indicated that year-to-year weight variation, though usually in a much narrower range than the between-individual variation, had a strong impact on the corresponding changes of serum concentrations of TC, HDL-C, and TG. This result supports the public health significance of intervention into weight control to prevent the development of atherogenic risks among a healthy workplace population.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.71.1-2.19
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 71, 号 1-2, p. 19-28, 発行日 2009-02
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/11333
識別子タイプ HDL
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