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Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese.
http://hdl.handle.net/2237/14922
http://hdl.handle.net/2237/14922bdba2002-c228-419c-ba83-8d494a89a231
名前 / ファイル | ライセンス | アクション |
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k9020.pdf (309.5 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2011-06-03 | |||||
タイトル | ||||||
タイトル | Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese. | |||||
言語 | en | |||||
著者 |
Muramatsu, Takashi
× Muramatsu, Takashi× Yatsuya, Hiroshi× Toyoshima, Hideaki× Sasaki, Satoshi× Li, Yuanying× Otsuka, Rei× Wada, Keiko× Hotta, Yo× Mitsuhashi, Hirotsugu× Matsushita, Kunihiro× Murohara, Toyoaki× Tamakoshi, Koji |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | This is the author's version of a work accepted for publication by Elsevier. Changes resulting from thepublishing process, including peer review, editing, corrections, structural formatting and other quality controlmechanisms, may not be reflected in this document. Changes may have been made to this work since it was submittedfor publication. The definitive version has been published in Preventive Medicine. v.50, n.5-6, 2010, 10.1016/j.ypmed.2010.02.014 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Nutritional sciences | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Polyunsaturated fatty acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | alpha-Linolenic acid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Insulin resistance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epidemiologic studies | |||||
抄録 | ||||||
内容記述 | Objective: To investigate the associations between dietary intake of n-3 polyunsaturated fatty acids (plant-derived alpha-linolenic acid: ALA, and marine-derived eicosapentaenoic and docosahexaenoic acid: EPA+DHA) and insulin resistance (IR) in a lean population with high n-3 PUFA intake. Method: We cross-sectionally studied 3383 Japanese local government workers aged 35-66 in 2002. IR was defined as the highest quartile of homeostasis model assessment, and nutrient intake was estimated from a diet history questionnaire. The odds ratios (ORs) of IR taking the lowest quartile of ALA or EPA+DHA intake as the reference were calculated by logistic regression analysis. Results: Mean age, body mass index (BMI), and dietary ALA, and median of dietary EPA +DHA were 47.9 years, 22.9 kg/m^2, and 1.90 g/day (0.88 %E) and 0.77 g/day (0.36 %E), respectively. The ORs of IR decreased across the quartiles of ALA intake (multivariate-adjusted OR for Q4 versus Q1 = 0.74, P for trend = 0.01) and the association was observed only in subjects with a BMI < 25 kg/m^2 (P for interaction = 0.033). However EPA+DHA showed no such associations consistently. Conclusion: Higher ALA intake was significantly associated with a lower prevalence of IR in normal weight individuals of middle-aged Japanese men and women. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | 名古屋大学博士学位論文 学位の種類 : 博士(医学)(課程) 学位授与年月日:平成23年3月25日 村松崇氏の博士論文として提出された | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.ypmed.2010.02.014 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0091-7435 | |||||
書誌情報 |
en : Preventive Medicine 巻 50, 号 5-6, p. 272-276, 発行日 2010-03-04 |
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学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 13901 | |||||
言語 | ja | |||||
学位授与機関名 | 名古屋大学 | |||||
言語 | en | |||||
学位授与機関名 | NAGOYA University | |||||
学位授与年度 | ||||||
学位授与年度 | 2009 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2010-03-04 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第9020号 | |||||
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値 | publisher | |||||
URI | ||||||
識別子 | http://dx.doi.org/10.1016/j.ypmed.2010.02.014 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/14922 | |||||
識別子タイプ | HDL |