ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "eaa4d62d-cffd-456a-bc54-17a444c6badc"}, "_deposit": {"id": "1370", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "1370"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00001370", "sets": []}, "author_link": ["3111", "3112", "3113", "3114", "3115", "3116"], "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1/2", "bibliographicPageEnd": "47", "bibliographicPageStart": "45", "bibliographicVolumeNumber": "46", "bibliographic_titles": [{"bibliographic_title": "Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Thyroid follicular neoplasm is commonly encountered in clinical medicine. However, it is difficult to pathologically differentiate benign from malignant tumors. Recently t (2,3)(ql3; p25), a translocation resulting in the generation of Pax8-PPARγ fusion gene has been reported in American patients with follicular carcinoma with high incidence suggesting that Pax8-PPARγ fusion mRNA could be a molecular marker for the diagnosis of follicular carcinoma. In this study we examined the expression of this fusion gene in follicular carcinomas in Japanese patients. Various thyroid nodules (follicular carcinoma, follicular adenoma, papillary carcinoma, adenomatous goiter and normal tissue) were obtained at surgery in our institute and total RNAs were used to detect the Pax8-PPARγ fusion mRNA by RT-PCR. In all the follicular carcinoma samples, Pax8-PPARγ fusion mRNA was not detected. In all the other samples the expression was also negative. On the other hand, wild type Pax8 mRNA was detected in all the samples and wild type PPARγ mRNA was detected in 83.3% of the follicular adenoma and the adenomatous goiter samples, in 100% of the follicular carcinoma, the papillary carcinoma and the normal tissue samples respectively. In contrast to the previous report, no expression of Pax8-PPARγ fusion gene was detected in follicular carcinomas. Ethnic background may affect the translocation on the pathogenesis.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "国立情報学研究所で電子化したコンテンツを使用している。", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/2780"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/envm.46.45", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Research Institute of Environmental Medicine, Nagoya University", "subitem_publisher_language": "en"}]}, "item_9_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN(print)", "attribute_value_mlt": [{"subitem_source_identifier": "02870517", "subitem_source_identifier_type": "PISSN"}]}, "item_9_text_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "HIBI, Yatsuka", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3111", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "NAGAYA, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3112", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KAMBE, Fukushi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3113", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "IMAI, Tsuneo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3114", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "FUNAHASHI, Hiroomi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3115", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "SEO, Hisao", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3116", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000034860.pdf", "filesize": [{"value": "376.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 376900.0, "url": {"label": "KJ00000034860.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/1370/files/KJ00000034860.pdf"}, "version_id": "8d416232-3cfa-4b46-9add-d00c5b2b0409"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Pax8", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PPARγ", "subitem_subject_scheme": "Other"}, {"subitem_subject": "thyroid", "subitem_subject_scheme": "Other"}, {"subitem_subject": "follicular carcinoma", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A specific Translocation of Chromosome 3 Generating Pax8-PPARg Fusion mRNA is Rare in Japanese Patients with Follicular Carcinoma", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "A specific Translocation of Chromosome 3 Generating Pax8-PPARg Fusion mRNA is Rare in Japanese Patients with Follicular Carcinoma", "subitem_title_language": "en"}]}, "item_type_id": "9", "owner": "1", "path": ["335"], "permalink_uri": "https://doi.org/10.18999/envm.46.45", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2006-01-05"}, "publish_date": "2006-01-05", "publish_status": "0", "recid": "1370", "relation": {}, "relation_version_is_last": true, "title": ["A specific Translocation of Chromosome 3 Generating Pax8-PPARg Fusion mRNA is Rare in Japanese Patients with Follicular Carcinoma"], "weko_shared_id": -1}
  1. F100 環境医学研究所
  2. F100b 紀要
  3. Environmental medicine : annual report of the Research Institute of Environmental Medicine
  4. 46(1-2)

A specific Translocation of Chromosome 3 Generating Pax8-PPARg Fusion mRNA is Rare in Japanese Patients with Follicular Carcinoma

https://doi.org/10.18999/envm.46.45
https://doi.org/10.18999/envm.46.45
ee6e343c-10b2-4e11-9a8f-2ca0525bb087
名前 / ファイル ライセンス アクション
KJ00000034860.pdf KJ00000034860.pdf (376.9 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2006-01-05
タイトル
タイトル A specific Translocation of Chromosome 3 Generating Pax8-PPARg Fusion mRNA is Rare in Japanese Patients with Follicular Carcinoma
言語 en
著者 HIBI, Yatsuka

× HIBI, Yatsuka

WEKO 3111

en HIBI, Yatsuka

Search repository
NAGAYA, Takashi

× NAGAYA, Takashi

WEKO 3112

en NAGAYA, Takashi

Search repository
KAMBE, Fukushi

× KAMBE, Fukushi

WEKO 3113

en KAMBE, Fukushi

Search repository
IMAI, Tsuneo

× IMAI, Tsuneo

WEKO 3114

en IMAI, Tsuneo

Search repository
FUNAHASHI, Hiroomi

× FUNAHASHI, Hiroomi

WEKO 3115

en FUNAHASHI, Hiroomi

Search repository
SEO, Hisao

× SEO, Hisao

WEKO 3116

en SEO, Hisao

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 Pax8
キーワード
主題Scheme Other
主題 PPARγ
キーワード
主題Scheme Other
主題 thyroid
キーワード
主題Scheme Other
主題 follicular carcinoma
抄録
内容記述 Thyroid follicular neoplasm is commonly encountered in clinical medicine. However, it is difficult to pathologically differentiate benign from malignant tumors. Recently t (2,3)(ql3; p25), a translocation resulting in the generation of Pax8-PPARγ fusion gene has been reported in American patients with follicular carcinoma with high incidence suggesting that Pax8-PPARγ fusion mRNA could be a molecular marker for the diagnosis of follicular carcinoma. In this study we examined the expression of this fusion gene in follicular carcinomas in Japanese patients. Various thyroid nodules (follicular carcinoma, follicular adenoma, papillary carcinoma, adenomatous goiter and normal tissue) were obtained at surgery in our institute and total RNAs were used to detect the Pax8-PPARγ fusion mRNA by RT-PCR. In all the follicular carcinoma samples, Pax8-PPARγ fusion mRNA was not detected. In all the other samples the expression was also negative. On the other hand, wild type Pax8 mRNA was detected in all the samples and wild type PPARγ mRNA was detected in 83.3% of the follicular adenoma and the adenomatous goiter samples, in 100% of the follicular carcinoma, the papillary carcinoma and the normal tissue samples respectively. In contrast to the previous report, no expression of Pax8-PPARγ fusion gene was detected in follicular carcinomas. Ethnic background may affect the translocation on the pathogenesis.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 国立情報学研究所で電子化したコンテンツを使用している。
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Research Institute of Environmental Medicine, Nagoya University
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/envm.46.45
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 02870517
書誌情報 en : Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University

巻 46, 号 1/2, p. 45-47, 発行日 2002-12
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/2780
識別子タイプ HDL
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 21:38:27.317458
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3