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A Combination of Eccentric Muscle Exercise and Repeated Cold Stress (RCS) Induced Prolonged Hyperalgesia : An Attempt to Develop an Animal Model of Chronic Muscle Pain
https://doi.org/10.18999/envm.46.74
https://doi.org/10.18999/envm.46.74296820be-2235-4687-8af4-4b08016296b3
名前 / ファイル | ライセンス | アクション |
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KJ00000034868.pdf (354.5 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-01-05 | |||||
タイトル | ||||||
タイトル | A Combination of Eccentric Muscle Exercise and Repeated Cold Stress (RCS) Induced Prolonged Hyperalgesia : An Attempt to Develop an Animal Model of Chronic Muscle Pain | |||||
言語 | en | |||||
著者 |
TAGUCHI, Toru
× TAGUCHI, Toru× SATO, Jun× MIZUMURA, Kazue |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | repeated cold stress | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | extensor digitorum longus muscle | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | delayed onset muscle soreness | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | eccentric contraction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mechanical pain threshold | |||||
抄録 | ||||||
内容記述 | Few studies have addressed the mechanism of chronic pain originating from musculoskeletal structure, in large part due to the lack of a reliable animal model of chronic muscle pain. The purpose of this study is to try to make an animal model of long-lasting muscle hyperalgesia, using a combination of eccentric muscle work and repeated cold stress (RCS). The mechanical withdrawal threshold in muscle was significantly decreased by RCS with or without eccentric muscle contraction (for at least 7 or 3 days after eccentric exercise or sham exercise, respectively). This result suggests that a combination of eccentric muscle work and RCS could prolong muscle hyperalgesia. However, the duration of the hyperalgesic state in this animal model was not considered long enough to be used in studies on the mechanism of chronic muscle pain. Further trials to elongate the period of hyperalgesia are needed. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | 国立情報学研究所で電子化したコンテンツを使用している。 | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Research Institute of Environmental Medicine, Nagoya University | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/envm.46.74 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 02870517 | |||||
書誌情報 |
en : Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University 巻 46, 号 1/2, p. 74-76, 発行日 2002-12 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/2788 | |||||
識別子タイプ | HDL |