{"_buckets": {"deposit": "e0aea4e3-a251-4268-9d04-31c995261989"}, "_deposit": {"id": "1391", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "1391"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00001391"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1/2", "bibliographicPageEnd": "111", "bibliographicPageStart": "109", "bibliographicVolumeNumber": "46", "bibliographic_titles": [{"bibliographic_title": "Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Our previous study showed that two components of the delayed rectifier potassium current, I_\u003cKr\u003e and I_\u003cKs\u003e, were heterogeneously distributed in right (RV) and left (LV) ventricles in rabbit hearts. However, the mechanisms of heterogeneous distribution of these channels were not known. In the present study, we investigated the encoding mRNA levels of I_\u003cKr\u003e (ERG) and I_\u003cKs\u003e (KVLQT1 and minK) in RV and LV. By using a quantitative real-time PCR method, we found mRNA levels were not significantly different between two ventricles in ERG (RV: 1103 \u00b1 218 molecules/10^5 GAPDH molecules, LV: 886 \u00b1 155, n=4), KVLQT1 (RV: 645 \u00b1 113, LV: 509 + 170, n=4) and minK (RV: 209 \u00b1 33, LV: 185 \u00b1 47, n=4). These results suggest that heterogeneous distribution of I_\u003cKr\u003e and I_\u003cKs\u003e in RV and LV could not be explained by the mRNA levels in ventricles. Other unknown factor may underlie this phenomenon.", "subitem_description_type": "Abstract"}]}, "item_9_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u56fd\u7acb\u60c5\u5831\u5b66\u7814\u7a76\u6240\u3067\u96fb\u5b50\u5316\u3057\u305f\u30b3\u30f3\u30c6\u30f3\u30c4\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3002", "subitem_description_type": "Other"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/2801"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/envm.46.109", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Research Institute of Environmental Medicine, Nagoya University"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "02870517", "subitem_source_identifier_type": "ISSN"}]}, "item_9_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "LU, Zhibo"}], "nameIdentifiers": [{"nameIdentifier": "3224", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HOJO, Mayumi"}], "nameIdentifiers": [{"nameIdentifier": "3225", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "YASUI, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "3226", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KODAMA, Itsuo"}], "nameIdentifiers": [{"nameIdentifier": "3227", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KAMIYA, Kaichiro"}], "nameIdentifiers": [{"nameIdentifier": "3228", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00000034881.pdf", "filesize": [{"value": "257.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 257800.0, "url": {"label": "KJ00000034881.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/1391/files/KJ00000034881.pdf"}, "version_id": "e557b7b3-adbd-4f03-a486-52e56dd11b00"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "rabbit", "subitem_subject_scheme": "Other"}, {"subitem_subject": "RV and LV", "subitem_subject_scheme": "Other"}, {"subitem_subject": "delayed rectifier K^+ current", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mRNA levels", "subitem_subject_scheme": "Other"}, {"subitem_subject": "regional distribution", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "mRNA Levels of ERG, KVLQT1 and minK in Rabbit Right and Left Ventricles", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "mRNA Levels of ERG, KVLQT1 and minK in Rabbit Right and Left Ventricles"}]}, "item_type_id": "9", "owner": "1", "path": ["329/333/334/335"], "permalink_uri": "https://doi.org/10.18999/envm.46.109", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2006-01-05"}, "publish_date": "2006-01-05", "publish_status": "0", "recid": "1391", "relation": {}, "relation_version_is_last": true, "title": ["mRNA Levels of ERG, KVLQT1 and minK in Rabbit Right and Left Ventricles"], "weko_shared_id": null}