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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 57(1-2)

MYOCARDIAL METABOLIC MARKERS OF TOTAL ISCHEMIA IN VITRO

https://doi.org/10.18999/nagjms.57.1-2.35
https://doi.org/10.18999/nagjms.57.1-2.35
3cbcbc9a-833c-4764-928c-7bb3c05aba94
名前 / ファイル ライセンス アクション
v57n12p35_42.pdf v57n12p35_42.pdf (416.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2012-02-03
タイトル
タイトル MYOCARDIAL METABOLIC MARKERS OF TOTAL ISCHEMIA IN VITRO
著者 KAKINUMA, YOSHIHIRO

× KAKINUMA, YOSHIHIRO

WEKO 98891

KAKINUMA, YOSHIHIRO

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MATSUBARA, TATSUAKI

× MATSUBARA, TATSUAKI

WEKO 98892

MATSUBARA, TATSUAKI

Search repository
HASHIMOTO, TATSUO

× HASHIMOTO, TATSUO

WEKO 98893

HASHIMOTO, TATSUO

Search repository
SAKAMOTO, NOBUO

× SAKAMOTO, NOBUO

WEKO 98894

SAKAMOTO, NOBUO

Search repository
キーワード
主題Scheme Other
主題 Total ischemia in vitro
キーワード
主題Scheme Other
主題 Succinate
キーワード
主題Scheme Other
主題 Lactate
キーワード
主題Scheme Other
主題 High energy phosphate
抄録
内容記述 The influence of total ischemia on the formation of products of anaerobic metabolism was investigated in canine hearts in vitro. Contents of organic acids were quantitatively analyzed by gas chromatography-mass spectrometry, and high energy phosphate compounds were determined using the luciferin-Iuciferase enzyme system. During a 10-min period of total ischemia, myocardial creatine phosphate significantly decreased, while ATP remained unchanged as compared with preischemic values. Both 10 min and 60 min of ischemia induced significant increase in tissue succinic acid levels. In contrast, a significant increase in myocardial lactic acid content was only induced with 60 min of ischemia. The data obtained indicate that the accumulation of succinic acid may be regarded as a potential metabolic marker of myocardial total ischemia.
内容記述タイプ Abstract
内容記述
内容記述 名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成5年9月14日 柿沼善弘氏の博士論文として提出された
内容記述タイプ Other
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.57.1-2.35
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5712/5712.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 57, 号 1-2, p. 35-42, 発行日 1994-03-25
著者版フラグ
値 publisher
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