{"_buckets": {"deposit": "1fec7cb1-96f0-4304-8b10-103512891673"}, "_deposit": {"id": "14449", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "14449"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00014449"}, "item_12_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1993-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "406", "bibliographicPageStart": "400", "bibliographicVolumeNumber": "42", "bibliographic_titles": [{"bibliographic_title": "Journal of Electron Microscopy"}]}]}, "item_12_date_granted_64": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5", "attribute_value_mlt": [{"subitem_dategranted": "1993-12-01"}]}, "item_12_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Bone morphogenetic protein (BMP) partially purified from bovine bone was implanted into the thigh muscles of AKR-strain mice to induce an ectopic endochondral ossification tissue. The extracellular matrix components around the hypertrophic chondrocytes in the induced tissue were examined by electron microscopy and immunohistochemistry for type I collagen. At 14 days after implantation, chondrocytes became hypertrophic with calcifying matrix around them. Some hypertrophic chondrocytes showed no degenerative appearances. They were ringed by a pericellular matrix with no metachromasia which was distinct from the metachromatic cartilage matrix. The localization of type I collagen was demonstrated by immuno-staining in this matrix. Ultrastructurally, ring-shaped matrix consisted of interwoven collagen fibrils on which a D-periodic banding pattern could be discerned. Immunoelectron microscopy demonstrated immunoreactivity of type I collagen on these fibrils. These results suggest that some of the BMP-induced hypertrophic chondrocytes maintain their activity and produce type I collagen-rich matrix before their lacunae are eroded.", "subitem_description_type": "Abstract"}]}, "item_12_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u540d\u53e4\u5c4b\u5927\u5b66\u535a\u58eb\u5b66\u4f4d\u8ad6\u6587 \u5b66\u4f4d\u306e\u7a2e\u985e : \u535a\u58eb(\u533b\u5b66)(\u8ab2\u7a0b) \u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5:\u5e73\u62106\u5e743\u670825\u65e5 \u670d\u90e8\u5b87\u6c0f\u306e\u535a\u58eb\u8ad6\u6587\u3068\u3057\u3066\u63d0\u51fa\u3055\u308c\u305f", "subitem_description_type": "Other"}]}, "item_12_dissertation_number_65": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u756a\u53f7", "attribute_value_mlt": [{"subitem_dissertationnumber": "13901\u7532\u7b2c2909\u53f7"}]}, "item_12_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "URI", "subitem_identifier_uri": "http://jmicro.oxfordjournals.org/content/42/6/400.abstract"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/16358"}]}, "item_12_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Oxford University Press"}]}, "item_12_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Journal of Electron Microscopy following peer review. The definitive publisher-authenticated version Journal of Electron Microscopy. v.42, n.6, 1993, p.400-406 is available online at: http://jmicro.oxfordjournals.org/content/42/6/400.abstract."}]}, "item_12_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_12_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-0744", "subitem_source_identifier_type": "ISSN"}]}, "item_12_text_63": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u5ea6", "attribute_value_mlt": [{"subitem_text_value": "1993"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hattori, Hisashi"}], "nameIdentifiers": [{"nameIdentifier": "44754", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawai, Michio"}], "nameIdentifiers": [{"nameIdentifier": "44755", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yasue, Kazuki"}], "nameIdentifiers": [{"nameIdentifier": "44756", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizutani, Hideki"}], "nameIdentifiers": [{"nameIdentifier": "44757", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Miya"}], "nameIdentifiers": [{"nameIdentifier": "44758", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kaneda, Toshio"}], "nameIdentifiers": [{"nameIdentifier": "44759", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hoshino, Takeshi"}], "nameIdentifiers": [{"nameIdentifier": "44760", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "k2909.pdf", "filesize": [{"value": "2.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2300000.0, "url": {"label": "k2909.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/14449/files/k2909.pdf"}, "version_id": "67fadbbe-12a5-4cef-9e01-16c8ef4a4253"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "bone morphogenetic protein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hypertrophic chondrocyte", "subitem_subject_scheme": "Other"}, {"subitem_subject": "immunoelectron microscopy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "type I collagen", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage"}]}, "item_type_id": "12", "owner": "1", "path": ["499/960/1165"], "permalink_uri": "http://hdl.handle.net/2237/16358", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2012-05-10"}, "publish_date": "2012-05-10", "publish_status": "0", "recid": "14449", "relation": {}, "relation_version_is_last": true, "title": ["A correlative immuno-light and electron microscopic study on the type I collagen in the bone morphogenetic protein-induced cartilage"], "weko_shared_id": null}