{"_buckets": {"deposit": "77b3f5ea-ea3e-4b65-abc2-ff73f5e8db34"}, "_deposit": {"id": "14780", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "14780"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00014780"}, "item_12_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1996-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "121", "bibliographicPageStart": "115", "bibliographicVolumeNumber": "60", "bibliographic_titles": [{"bibliographic_title": "Journal of Surgical Research"}]}]}, "item_12_date_granted_64": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5", "attribute_value_mlt": [{"subitem_dategranted": "1996-01-01"}]}, "item_12_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Patients with pancreaticobiliary maljunction without bile duct dilatation (PBMWBDD) develop gallbladder carcinoma frequently. No models of PBMWBDD exist, and no previous studies have clearly demonstrated changes in the gallbladder relating to carcinogenesis. We, therefore, examined the cell kinetics of the gallbladder epithelium in a new experimental model of PBMWBDD. A cat model was produced by performing choledocho-pancreatic side-to-side ductal anastomosis in nine animals. Five cats, in which the choledocho-pancreatic ducts were exposed only, served as controls. After 6 months, the gallbladders of these cats were removed and stained with anti-proliferating cell nuclear antigen (PCNA) antibody (PC10, Dako). The labeling index (LI) was determined from the percentage of positive nuclei in three microscopic fields. The diameter of the common bile duct was not different between the models and the controls. In the models, the number of PCNA positive cells was significantly increased. The mean (\u00b1 standard deviation) PCNA LI was 28.1 \u00b1 12.2% in the models and 4.3 \u00b1 1.6% in the controls (P\u003c 0.01). These studies clearly indicate that this model is suitable for studying PBMWBDD and that PBMWBDD has a prominent proliferating effect on the gallbladder epithelium which may play an important role in gallbladder carcinogenesis.", "subitem_description_type": "Abstract"}]}, "item_12_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u540d\u53e4\u5c4b\u5927\u5b66\u535a\u58eb\u5b66\u4f4d\u8ad6\u6587 \u5b66\u4f4d\u306e\u7a2e\u985e : \u535a\u58eb(\u533b\u5b66)(\u8ab2\u7a0b) \u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5:\u5e73\u62107\u5e743\u670827\u65e5 \u91d1\u5b50\u5065\u4e00\u6717\u6c0f\u306e\u535a\u58eb\u8ad6\u6587\u3068\u3057\u3066\u63d0\u51fa\u3055\u308c\u305f", "subitem_description_type": "Other"}]}, "item_12_dissertation_number_65": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u756a\u53f7", "attribute_value_mlt": [{"subitem_dissertationnumber": "13901\u7532\u7b2c3182\u53f7"}]}, "item_12_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://dx.doi.org/10.1006/jsre.1996.0019"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/16712"}]}, "item_12_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_12_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "This is the author\u0027s version of a work that was accepted for publication in Journal of Surgical Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Surgical Research. v.60, n.1, 1996, p.115\u2013121 http://dx.doi.org/10.1006/jsre.1996.0019"}]}, "item_12_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_12_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0022-4804", "subitem_source_identifier_type": "ISSN"}]}, "item_12_text_63": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u5ea6", "attribute_value_mlt": [{"subitem_text_value": "1995"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kaneko, Kenitiro"}], "nameIdentifiers": [{"nameIdentifier": "45628", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ando, Hisami"}], "nameIdentifiers": [{"nameIdentifier": "45629", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umeda, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "45630", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Murahashi, Osamu"}], "nameIdentifiers": [{"nameIdentifier": "45631", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hiraiwa, Katsumasa"}], "nameIdentifiers": [{"nameIdentifier": "45632", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Niimi, Norihiro"}], "nameIdentifiers": [{"nameIdentifier": "45633", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hossain, Moazzem"}], "nameIdentifiers": [{"nameIdentifier": "45634", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Takahiro"}], "nameIdentifiers": [{"nameIdentifier": "45635", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "k3182.pdf", "filesize": [{"value": "5.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 5000000.0, "url": {"label": "k3182.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/14780/files/k3182.pdf"}, "version_id": "343d78e3-a316-4cee-b336-e00ed18f739d"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Choledochal cyst", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Bile ducts", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pancreatic ducts", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Gallbladder neoplasms", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cell cycle", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PCNA", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "A New Model for Pancreaticobiliary Maljunction without Bile Duct Dilatation: Demonstration of Cell Proliferation in the Gallbladder Epithelium", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "A New Model for Pancreaticobiliary Maljunction without Bile Duct Dilatation: Demonstration of Cell Proliferation in the Gallbladder Epithelium"}]}, "item_type_id": "12", "owner": "1", "path": ["499/960/1165"], "permalink_uri": "http://hdl.handle.net/2237/16712", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2012-08-20"}, "publish_date": "2012-08-20", "publish_status": "0", "recid": "14780", "relation": {}, "relation_version_is_last": true, "title": ["A New Model for Pancreaticobiliary Maljunction without Bile Duct Dilatation: Demonstration of Cell Proliferation in the Gallbladder Epithelium"], "weko_shared_id": null}