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  1. C100 医学部/医学系研究科
  2. C100d 学位論文
  3. 博士論文(医博・論医博)

Proliferating cell nuclear antigen expression in papillary thyroid carcinoma

http://hdl.handle.net/2237/16718
http://hdl.handle.net/2237/16718
896aa5eb-1075-45f4-b321-8acaaa9659ba
名前 / ファイル ライセンス アクション
o5153.pdf o5153.pdf (741.4 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2012-08-21
タイトル
タイトル Proliferating cell nuclear antigen expression in papillary thyroid carcinoma
言語 en
著者 Ando, H

× Ando, H

WEKO 45658

en Ando, H

Search repository
Funahashi, H

× Funahashi, H

WEKO 45659

en Funahashi, H

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Ito, M

× Ito, M

WEKO 45660

en Ito, M

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Imai, T

× Imai, T

WEKO 45661

en Imai, T

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Takagi, H

× Takagi, H

WEKO 45662

en Takagi, H

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
抄録
内容記述 AIMS: To correlate the expression of proliferating cell nuclear antigen (PCNA) with various clinicopathological features of papillary thyroid carcinoma. METHODS: Sections from 131 formalin fixed, paraffin wax embedded papillary thyroid carcinomas were stained with a monoclonal antibody (PC10) directed against PCNA using the avidin-biotin immunoperoxidase (ABC) method. PCNA immunoreactivity was based on the PCNA labelling index (LI) following evaluation of at least 1000 tumour cells, and expressed as follows: grade A (LI < 10%), grade B (10% < or = LI < 25%), and grade C (LI > or = 25%). The relation between PCNA expression in these three groups and other clinicopathological factors, such as sex, age, tumour size, nodal metastases, and histological differentiation, were examined. RESULTS: Based on the labelling index, 57 (43.5%) cases were graded as A, 46 (35.1%) as B, and 28 (21.4%) as C. The female-:male ratios were 6.13:1 for group A, 2.83:1 for group B, and 2.11:1 for group C. The mean (SD) ages of the patients were 39.0 (16.1) in group A, 53.5 (14.4) in group B, and 55.8 (13.3) years in group C. The correlation between age and PCNA grade was strongest in women. CONCLUSIONS: PCNA immunoreactivity is correlated with sex and age in patients with papillary thyroid tumours.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 名古屋大学博士学位論文 学位の種類 : 博士(医学)(論文) 学位授与年月日:平成9年2月20日 安藤広幸氏の博士論文として提出された
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 the BMJ Publishing Group
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_db06
タイプ doctoral thesis
ISSN
収録物識別子タイプ PISSN
収録物識別子 0021-9746
書誌情報 en : Journal of Clinical Pathology

巻 49, 号 8, p. 657-659, 発行日 1996-08
学位名
言語 ja
学位名 博士(医学)
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 13901
言語 ja
学位授与機関名 名古屋大学
言語 en
学位授与機関名 NAGOYA University
学位授与年度
学位授与年度 1996
学位授与年月日
学位授与年月日 1996-08-01
学位授与番号
学位授与番号 乙第5153号
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/16718
識別子タイプ HDL
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