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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 36(2-4)

Thermoregulatory Responses in Normal and Cold Acclimated Rabbits

https://doi.org/10.18999/nagjms.36.2-4.79
https://doi.org/10.18999/nagjms.36.2-4.79
19cf33ea-965d-483e-b2d2-ac576ed0ef3f
名前 / ファイル ライセンス アクション
v36n24p79_89.pdf v36n24p79_89.pdf (752.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-01-18
タイトル
タイトル Thermoregulatory Responses in Normal and Cold Acclimated Rabbits
著者 NAGASAKA, TETSUO

× NAGASAKA, TETSUO

WEKO 46620

NAGASAKA, TETSUO

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抄録
内容記述 Metabolic rate (M), tissue conductance (k), rectal (Tre) and mean skin temperature (Ts) were measured in normal (CONT) and cold acclimated (CA) rabbits after steady state for a given ambient temperature (Tα) from 5 to 35°C. Below Tα=15°C, Tre of CONT decreased considerably, while Tre of CA was maintained within a normal range. The rate of change in Ts for each degree change in Tα (below Tα=15°C) was smaller in CA. M, always higher in CA than in CONT at any Tα, increased more than twice the basal value (2.54 W/kg±0.06 SE for CONT and 2.85 W/kg±0.07 SE for CA at Tα=25°C) during cold exposure (Tα= 5°C). Though k was relatively constant at Tα=25-5°C, it increased considerably at Tα=35°C. The value for CA was higher than that for CONT at any Tα. Perfusion of norepinephrine (NE, 3 μg/kg·min for 30-min) in curarized rabbits caused bradycardia, which was more conspicuous in CONT. NE caused an increase in M (ca. 18%) in CA without any change in CONT (p<0.01). The increase in M was not limited to the duration of NE perfusion. NE did not change body temperatures except for slight rise of Ts in CA. During cold exposure, body temperatures decreased continuously in the curarized rabbits. M increased slightly during the initial 30-40 min of cold exposure in CA. The results confirmed that the rabbit acclimates to cold by enhancing nonshivering thermogenesis mediated by NE, as well as by improving insulation.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.36.2-4.79
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 36, 号 2-4, p. 79-89, 発行日 1974-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/3624/3624.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17292
識別子タイプ HDL
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