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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 46(1-4)

Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer

https://doi.org/10.18999/nagjms.46.1-4.117
https://doi.org/10.18999/nagjms.46.1-4.117
df4d556f-e211-4443-9060-862148a07bd2
名前 / ファイル ライセンス アクション
v46n14p117_123.pdf v46n14p117_123.pdf (532.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-02-08
タイトル
タイトル Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer
著者 KUSUGAMI, KAZUO

× KUSUGAMI, KAZUO

WEKO 98700

KUSUGAMI, KAZUO

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MORISE, KIMITOMO

× MORISE, KIMITOMO

WEKO 98701

MORISE, KIMITOMO

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KATO, HAJIME

× KATO, HAJIME

WEKO 98702

KATO, HAJIME

Search repository
キーワード
主題Scheme Other
主題 Gamma Interferon
キーワード
主題Scheme Other
主題 Gastric Cancer
キーワード
主題Scheme Other
主題 Cell-mediated Immunity
キーワード
主題Scheme Other
主題 Quantitative Parameter
抄録
内容記述 The production of gamma interferon (IFN-γ) by peripheral blood lymphocytes was studied in 38 patients with gastric cancer. Purified protein derivative (PPD) as a specific antigen and three kinds of mitogens, phytohemagglutinin-P (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM), were used as IFN-γ inducers. IFN-γ production by lymphocytes was markedly reduced in patients with gastric cancer when these inducers were used. Reduction of IFN-γ production was observed more often in patients of Stage IV than in those of Stage I when PPD or Con A was used. PPD-induced IFN-γ production significantly increased in patients who were operated on curatively, while it decreased in those who were operated on noncuratively. IFN-γ production by lymphocytes, especially when PPD is used as an IFN-γ inducer, reflects cell-mediated immunity in patients with gastric cancer. It may be useful as quantitative parameter to predict therapeutic effects and prognosis in cancer patients.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.46.1-4.117
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4614/4614.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 46, 号 1-4, p. 117-123, 発行日 1984-03
著者版フラグ
値 publisher
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