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Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer
https://doi.org/10.18999/nagjms.46.1-4.117
https://doi.org/10.18999/nagjms.46.1-4.117df4d556f-e211-4443-9060-862148a07bd2
名前 / ファイル | ライセンス | アクション |
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v46n14p117_123.pdf (532.5 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-02-08 | |||||
タイトル | ||||||
タイトル | Gamma Interferon Production by Peripheral Blood Lymphocytes in Patients with Gastric Cancer | |||||
言語 | en | |||||
著者 |
KUSUGAMI, KAZUO
× KUSUGAMI, KAZUO× MORISE, KIMITOMO× KATO, HAJIME |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gamma Interferon | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gastric Cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cell-mediated Immunity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Quantitative Parameter | |||||
抄録 | ||||||
内容記述 | The production of gamma interferon (IFN-γ) by peripheral blood lymphocytes was studied in 38 patients with gastric cancer. Purified protein derivative (PPD) as a specific antigen and three kinds of mitogens, phytohemagglutinin-P (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM), were used as IFN-γ inducers. IFN-γ production by lymphocytes was markedly reduced in patients with gastric cancer when these inducers were used. Reduction of IFN-γ production was observed more often in patients of Stage IV than in those of Stage I when PPD or Con A was used. PPD-induced IFN-γ production significantly increased in patients who were operated on curatively, while it decreased in those who were operated on noncuratively. IFN-γ production by lymphocytes, especially when PPD is used as an IFN-γ inducer, reflects cell-mediated immunity in patients with gastric cancer. It may be useful as quantitative parameter to predict therapeutic effects and prognosis in cancer patients. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.46.1-4.117 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/4614/4614.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 46, 号 1-4, p. 117-123, 発行日 1984-03 |
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著者版フラグ | ||||||
値 | publisher |