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Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD
https://doi.org/10.18999/nagjms.50.1-4.17
1bc28aef-557e-43b3-ab65-dd8e3947e5e1
名前 / ファイル | ライセンス | アクション | |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-02-13 | |||||
タイトル | ||||||
タイトル | Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD | |||||
著者 |
IINUMA, MASAO
× IINUMA, MASAO× KATO, KATSUYA× AOKI, HIIZU× ANDO, KOICHI× NAKASHIMA, IZUMI× YOSHII, SAIJI |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | BRM | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | PPD-V | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | suppression of tumor markers | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | adjuvant immunotherapy | |||||
抄録 | ||||||
内容記述 | Forty-two patients with neoplastic diseases received intravenous administration of PPD (PPD-V), and tumor markers were monitored between January, 1986 and February, 1987. Tumor markers such as CEA, AFP, SCC, CA125, IAP and polyamines decreased significantly following the PPD-V therapy. In some cases, PPD-V therapy also reduced the progression of clinical manifestation of the disease. We could not detect serum IL-2 or TNF activity. IL-2 production and sensitivity of lymphocytes were also undetectable. Intravenous administration of PPD was concluded to be effective as an adjuvant therapy against human neoplastic disease. A reduction of tumor markers was observed in 19 of the 26 assessable patients (73%). We discussed the mechanism of suppression of tumor markers by PPD-V therapy. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.50.1-4.17 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 50, 号 1-4, p. 17-26, 発行日 1988-03 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5014/5014.html | |||||
識別子タイプ | URI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/17502 | |||||
識別子タイプ | HDL |