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Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD
https://doi.org/10.18999/nagjms.50.1-4.17
https://doi.org/10.18999/nagjms.50.1-4.171bc28aef-557e-43b3-ab65-dd8e3947e5e1
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v50n14p17_26.pdf (703.2 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-02-13 | |||||
| タイトル | ||||||
| タイトル | Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD | |||||
| 言語 | en | |||||
| 著者 |
IINUMA, MASAO
× IINUMA, MASAO× KATO, KATSUYA× AOKI, HIIZU× ANDO, KOICHI× NAKASHIMA, IZUMI× YOSHII, SAIJI |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | BRM | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | PPD-V | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | suppression of tumor markers | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | adjuvant immunotherapy | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Forty-two patients with neoplastic diseases received intravenous administration of PPD (PPD-V), and tumor markers were monitored between January, 1986 and February, 1987. Tumor markers such as CEA, AFP, SCC, CA125, IAP and polyamines decreased significantly following the PPD-V therapy. In some cases, PPD-V therapy also reduced the progression of clinical manifestation of the disease. We could not detect serum IL-2 or TNF activity. IL-2 production and sensitivity of lymphocytes were also undetectable. Intravenous administration of PPD was concluded to be effective as an adjuvant therapy against human neoplastic disease. A reduction of tumor markers was observed in 19 of the 26 assessable patients (73%). We discussed the mechanism of suppression of tumor markers by PPD-V therapy. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.50.1-4.17 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5014/5014.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 50, 号 1-4, p. 17-26, 発行日 1988-03 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/17502 | |||||
| 識別子タイプ | HDL | |||||
