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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 50(1-4)

Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD

https://doi.org/10.18999/nagjms.50.1-4.17
1bc28aef-557e-43b3-ab65-dd8e3947e5e1
名前 / ファイル ライセンス アクション
v50n14p17_26.pdf v50n14p17_26.pdf (703.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-02-13
タイトル
タイトル Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD
著者 IINUMA, MASAO

× IINUMA, MASAO

WEKO 47193

IINUMA, MASAO

Search repository
KATO, KATSUYA

× KATO, KATSUYA

WEKO 47194

KATO, KATSUYA

Search repository
AOKI, HIIZU

× AOKI, HIIZU

WEKO 47195

AOKI, HIIZU

Search repository
ANDO, KOICHI

× ANDO, KOICHI

WEKO 47196

ANDO, KOICHI

Search repository
NAKASHIMA, IZUMI

× NAKASHIMA, IZUMI

WEKO 47197

NAKASHIMA, IZUMI

Search repository
YOSHII, SAIJI

× YOSHII, SAIJI

WEKO 47198

YOSHII, SAIJI

Search repository
キーワード
主題Scheme Other
主題 BRM
キーワード
主題Scheme Other
主題 PPD-V
キーワード
主題Scheme Other
主題 suppression of tumor markers
キーワード
主題Scheme Other
主題 adjuvant immunotherapy
抄録
内容記述 Forty-two patients with neoplastic diseases received intravenous administration of PPD (PPD-V), and tumor markers were monitored between January, 1986 and February, 1987. Tumor markers such as CEA, AFP, SCC, CA125, IAP and polyamines decreased significantly following the PPD-V therapy. In some cases, PPD-V therapy also reduced the progression of clinical manifestation of the disease. We could not detect serum IL-2 or TNF activity. IL-2 production and sensitivity of lymphocytes were also undetectable. Intravenous administration of PPD was concluded to be effective as an adjuvant therapy against human neoplastic disease. A reduction of tumor markers was observed in 19 of the 26 assessable patients (73%). We discussed the mechanism of suppression of tumor markers by PPD-V therapy.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.50.1-4.17
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 50, 号 1-4, p. 17-26, 発行日 1988-03
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/5014/5014.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/17502
識別子タイプ HDL
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