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Application of Heat to Cancer Chemotherapy : Experimental Studies
https://doi.org/10.18999/nagjms.30.1.1
https://doi.org/10.18999/nagjms.30.1.1a4e5e6f8-e6c9-46d0-b7dc-eaae85ae7247
名前 / ファイル | ライセンス | アクション |
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v30n1p1_21.pdf (3.6 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-09-25 | |||||
タイトル | ||||||
タイトル | Application of Heat to Cancer Chemotherapy : Experimental Studies | |||||
言語 | en | |||||
著者 |
SUZUKI, KAZUO
× SUZUKI, KAZUO |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Many facts have been reported, that heat destroys some tumors and potentiates the effects of radiation on tumors. Recently, it was also showed in vitro, that heat enhances the effects of anticancer drugs. The first part of this work was designed to define this in vivo. Heat applied for 30 minutes inhibited the growth of Yoshida solid sarcoma implanted on the feet of rats and enhanced the Nitromin effectiveness on them at more than 42℃. Heat has been applied also to the regional perfusions to promote the action of chemotherapeutic agents. In the second part of this work, with the hyperthermic perfusions of the hind limbs of dogs, the tissue temperature could be elevated to up to 42℃ without complications. These perfusions produced homogeneous distribution of temperature and did not affect the systemic temperature. The hyperthermic perfusion, therefore, was a most suitable method for local heating in combination with cancer chemotherapy. At the same time, elevated temperatures enhanced the action of Nitromin on normal tissue. The determination of the dose of drug should be carefully considered in hyperthermic perfusion. | |||||
言語 | en | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.30.1.1 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/301/301.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 30, 号 1, p. 1-21, 発行日 1967-06 |
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著者版フラグ | ||||||
値 | publisher |