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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 30(1)

Application of Heat to Cancer Chemotherapy : Experimental Studies

https://doi.org/10.18999/nagjms.30.1.1
https://doi.org/10.18999/nagjms.30.1.1
a4e5e6f8-e6c9-46d0-b7dc-eaae85ae7247
名前 / ファイル ライセンス アクション
v30n1p1_21.pdf v30n1p1_21.pdf (3.6 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-09-25
タイトル
タイトル Application of Heat to Cancer Chemotherapy : Experimental Studies
著者 SUZUKI, KAZUO

× SUZUKI, KAZUO

WEKO 93946

SUZUKI, KAZUO

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抄録
内容記述 Many facts have been reported, that heat destroys some tumors and potentiates the effects of radiation on tumors. Recently, it was also showed in vitro, that heat enhances the effects of anticancer drugs. The first part of this work was designed to define this in vivo. Heat applied for 30 minutes inhibited the growth of Yoshida solid sarcoma implanted on the feet of rats and enhanced the Nitromin effectiveness on them at more than 42℃. Heat has been applied also to the regional perfusions to promote the action of chemotherapeutic agents. In the second part of this work, with the hyperthermic perfusions of the hind limbs of dogs, the tissue temperature could be elevated to up to 42℃ without complications. These perfusions produced homogeneous distribution of temperature and did not affect the systemic temperature. The hyperthermic perfusion, therefore, was a most suitable method for local heating in combination with cancer chemotherapy. At the same time, elevated temperatures enhanced the action of Nitromin on normal tissue. The determination of the dose of drug should be carefully considered in hyperthermic perfusion.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.30.1.1
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/301/301.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 30, 号 1, p. 1-21, 発行日 1967-06
著者版フラグ
値 publisher
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