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  1. C100 医学部/医学系研究科
  2. C100b 刊行物
  3. Nagoya journal of medical science
  4. 30(2)

Studies on Thromboplastin Generation Test

https://doi.org/10.18999/nagjms.30.2.193
https://doi.org/10.18999/nagjms.30.2.193
03842352-75be-4bbd-8e1e-291be65a435a
名前 / ファイル ライセンス アクション
v30n2p193_209.pdf v30n2p193_209.pdf (1.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-09-25
タイトル
タイトル Studies on Thromboplastin Generation Test
言語 en
著者 SHIOYA, MASAO

× SHIOYA, MASAO

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en SHIOYA, MASAO

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
抄録
内容記述タイプ Abstract
内容記述 In this paper, an attempt to devise a most satisfactory method of thromboplastin generation test (TGT) was made and the results were as follows : 1) As anticoagulant for the preparation of plasma, sodium citrate is superior to potassium oxalate, because the various factors in the former are more stable than those in oxalated plasma. 2) In adsorption of plasma, BaSO4 and Al(OH)3-gel are both useful. In citrated plasma, the optimum dose was 200 mg/ml and preferable adsorption time at 37°C ranged from 5 to 20 minutes with BaSO4,, and with AL(OH)3 0.03 ml/ml, 1-3 minutes. However, there is need to use BaSO4, of purity above 99% and with grain size mostly of 1-2µ 3) Serum should be separated 1 hour after initiation of the incubation in case of normal whole blood clotting time, and 3 hours after in hemophiliacs. There is no need to activate the serum with glass beads. 4) The optimum concentration of platelet suspension was found to be 200,000- 300,000/cmm and washing of platelets should be made for at least 4 times. But in general, platelet substitutes should be used, and the potency of such substitutes should preferably possess minimal substrate clotting time of about 10 seconds. 5) The normal value of TGT was 9.97± 0.938 seconds for the minimal substrate clotting time, or 100± 23.3% in thromboplastic activity. 6) The standard dilution curve of TGT can be plotted linearly on a bilogarithmic scale and they should be prepared for each time of measurement, and the results of TGT indicated by percentages of the normal value.
言語 en
出版者
出版者 Nagoya University School of Medicine
言語 en
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.30.2.193
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/302/302.html
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 30, 号 2, p. 193-209, 発行日 1967-09
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