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Studies on Lipogenesis in Hereditary Obese-Hyperglycemic Mice (KK Strain)
https://doi.org/10.18999/nagjms.32.1.129
https://doi.org/10.18999/nagjms.32.1.129d3ca19e9-836e-4728-be0c-82bf2e6ee63d
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2013-10-04 | |||||
タイトル | ||||||
タイトル | Studies on Lipogenesis in Hereditary Obese-Hyperglycemic Mice (KK Strain) | |||||
言語 | en | |||||
著者 |
KATO, KANEFUSA
× KATO, KANEFUSA |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Fatty acid synthesis in KK mouse, which exhibits a hereditary obese-hyperglycemic syndrome, was studied. Incorporation of [U-14C] glucose into liver fatty acid in vivo was more than four times higher in KK compared with control mice (CF1), but no significantly increased incorporation was observed into carcass fatty acid. Incorporation of [1-14C] acetate into liver fatty acid in vivo was also elevated (5 fold) in KK mice. Fatty acid synthesis from acetate by liver slices of KK mice was about three times higher than that of control. However, the con- version of acetate into fatty acid in adipose tissues from KK mice in vitro was lower than that of control. Level of Liver acetyl CoA carboxylase was twice as high in KK, but with the activity of liver citrate-cleavage enzyme, no difference was observed between KK and control mouse. Mechanisms of hyperlipogenesis in the liver of KK mouse were discussed in relation to hyperinsulinemia and hyperglycemia. | |||||
言語 | en | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.32.1.129 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/321/321.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 32, 号 1, p. 129-141, 発行日 1969-07 |
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著者版フラグ | ||||||
値 | publisher |