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Detection of Serum Antibodies to Aminopyrine or its Derivatives by a Passive Hemagglutination Assay Method
https://doi.org/10.18999/nagjms.32.3-4.379
https://doi.org/10.18999/nagjms.32.3-4.379718fc02e-e2ea-4773-9fac-d605c9ca5a33
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
v32n34p379_386.pdf (979.8 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2013-10-04 | |||||
| タイトル | ||||||
| タイトル | Detection of Serum Antibodies to Aminopyrine or its Derivatives by a Passive Hemagglutination Assay Method | |||||
| 言語 | en | |||||
| 著者 |
HASEGAWA, HITOSHI
× HASEGAWA, HITOSHI× KAMIYA, OSAMU× NAGASE, HIROAKI× TAKIKAWA, KIYOHARU |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | An attempt has been made to detect antibodies to aminopyrine or its derivatives (pyrazolone derivatives) with a passive hemagglutination assay system. Formalinized red blood cells were sensitized by coupling diazotized 4-aminoantipyrine to the surface membrane. With this method, circulating antibodies were detected in a patient with aminopyrine-induced agranulocytosis. Serial determinations revealed that the concentration of antibody increased rapidly after the onset of clinical manifestations, reaching a maximum in about a week, and thereafter began to fall off gradually. The presence of antibody was found in 32 sera of 75 patients with a history of skin reaction due to aminopyrine or its analogues and in 15 sera of 62 control subjects having no such history. The highest hemagglutination titer was 1 : 16. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.32.3-4.379 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 32, 号 3-4, p. 379-386, 発行日 1970-03 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
