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LIMBIC ENCEPHALITIS ASSOCIATED WITH RELAPSING POLYCHONDRITIS RESPONDED TO INFLIXIMAB AND MAINTAINED ITS CONDITION WITHOUT RECURRENCE AFTER DISCONTINUATION : A CASE REPORT AND REVIEW OF THE LITERATURE
https://doi.org/10.18999/nagjms.76.3-4.361
https://doi.org/10.18999/nagjms.76.3-4.3617cb6195e-f247-45b0-aa34-95585a9ccfee
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
23_Kondo.pdf (8.4 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-09-08 | |||||
| タイトル | ||||||
| タイトル | LIMBIC ENCEPHALITIS ASSOCIATED WITH RELAPSING POLYCHONDRITIS RESPONDED TO INFLIXIMAB AND MAINTAINED ITS CONDITION WITHOUT RECURRENCE AFTER DISCONTINUATION : A CASE REPORT AND REVIEW OF THE LITERATURE | |||||
| 言語 | en | |||||
| 著者 |
KONDO, TAKESHI
× KONDO, TAKESHI× FUKUTA, MAMIKO× TAKEMOTO, AYUMU× TAKAMI, YUICHIRO× SATO, MOTOKI× TAKAHASHI, NORIYUKI× SUZUKI, TOMIO× SATO, JUICHI× ATSUTA, NAOKI× SOBUE, GEN× TAKAHASHI, YUKITOSHI× BAN, NOBUTARO |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | relapsing polychondritis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | limbic encephalitis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | infliximab | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | anti-tumor necrosis factor-alpha agent | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | therapy discontinuation | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Central nervous system (CNS) manifestations are rare complications of relapsing polychondritis (RP). The majority of patients respond well to glucocorticoid therapy, but need to maintain it. Some patients are refractory to initial glucocorticoid therapy and to additional immunosuppressants, and end up with an outcome worse than at therapy initiation. The standardized therapeutic protocol for this condition has not been established. The effects of anti-tumor necrosis factor (TNF) -α agents have been reported recently. We experienced a patient with RP and limbic encephalitis who was refractory to initial high-dose glucocorticoid, but subsequently responded to infliximab and did not show deterioration of signs and symptoms after stopping therapy. We report this case together with a systematic literature review. This is the first case report of RP with CNS manifestations successfully treated by an anti-TNF-α agent without recurrence after discontinuation. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.76.3-4.361 | |||||
| ID登録タイプ | JaLC | |||||
| 関連情報 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/7634/7634.html | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 76, 号 3-4, p. 361-368, 発行日 2014-08 |
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| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/20556 | |||||
| 識別子タイプ | HDL | |||||
