{"_buckets": {"deposit": "442c720c-44e4-4d2d-ac39-2c20b291035f"}, "_deposit": {"id": "2001662", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2001662"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:02001662", "sets": ["1638493189962"]}, "author_link": [], "control_number": "2001662", "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2021-11", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "825", "bibliographicPageStart": "811", "bibliographicVolumeNumber": "83", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "The Tokai Study Group for Therapeutic Radiology and Oncology (TOSTRO) started managing T1 glottic cancer using 2.25 Gy/fraction radiotherapy in 2011. The aim was to evaluate the local control (LC) rate and toxicity with 2.25-Gy radiotherapy in clinical practice and identify prognostic factors.The eligibility criteria were T1 glottic squamous cell carcinoma patients with age ≥20 years, treated with 2.25 Gy/fraction without chemotherapy between 2011 and 2017. LC rates were evaluated based on age, performance status, sex, T-category, tumor type (ulcerative or non-ulcerative), presence of anterior commissure invasion, tumor size, X-ray beam energy, and overall treatment time. Acute and late adverse events were evaluated using CTCAE version 4.0. A total of 202 patients were enrolled. The median follow-up period was 34.2 months. The 2- and 4-year LC rates were 93.8% and 93.1%, respectively. There was a significant difference in the LC rate between non-ulcerative type and ulcerative type (95.2% vs. 74.1% at 2 years, 94.4% vs. 74.1% at 4 years; p = 0.01). On univariate analysis, only tumor type was significantly correlated with a poor LC rate (hazard ratio 4.3; 95% confidence interval 1.2–15.4; p = 0.03). Acute grade 3 adverse events occurred in 17 patients. However, no late adverse events of grade 3 or higher have occurred to date. T1 glottic cancer treatment outcomes using hypofractionated radiotherapy with 2.25 Gy/fraction in clinical practice were comparable to previously reported results. However, ulcerative type tumor was associated with a poor LC rate.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}, {"subitem_description": "This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).", "subitem_description_language": "en", "subitem_description_type": "Other"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.83.4.811", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University Graduate School of Medicine, School of Medicine", "subitem_publisher_language": "en"}]}, "item_9_relation_43": {"attribute_name": "関連情報", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/834.html", "subitem_relation_type_select": "URI"}}]}, "item_9_source_id_7": {"attribute_name": "収録物識別子", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "PISSN"}, {"subitem_source_identifier": "2186-3326", "subitem_source_identifier_type": "EISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Oie, Yumi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Itoh, Yoshiyuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kawamura, Mariko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Takase, Yuuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Murao, Takayuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Ishihara, Shunichi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nomoto, Yoshihito", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hirasawa, Naoki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Asano, Akiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yamakawa, Kouji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Ito, Junji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kinoshita, Fumie", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Naganawa, Shinji", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2021-12-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "15_Oie.pdf", "filesize": [{"value": "1.6 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "application/pdf", "size": 1600000.0, "url": {"objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/2001662/files/15_Oie.pdf"}, "version_id": "60d3a179-f7ef-405e-8059-b9aebdc804a5"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "T1 glottic cancer", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hypofractionated radiotherapy", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "2.25 Gy", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ulcerative tumor type", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Poor local control of ulcerative T1 glottic cancer treated with 2.25-Gy per fraction radiotherapy", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Poor local control of ulcerative T1 glottic cancer treated with 2.25-Gy per fraction radiotherapy", "subitem_title_language": "en"}]}, "item_type_id": "40001", "owner": "1", "path": ["1638493189962"], "permalink_uri": "https://doi.org/10.18999/nagjms.83.4.811", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-12-03"}, "publish_date": "2021-12-03", "publish_status": "0", "recid": "2001662", "relation": {}, "relation_version_is_last": true, "title": ["Poor local control of ulcerative T1 glottic cancer treated with 2.25-Gy per fraction radiotherapy"], "weko_shared_id": -1}