{"_buckets": {"deposit": "134d26aa-2603-4d2a-a0b6-42a3b33dec5f"}, "_deposit": {"created_by": 17, "id": "2002875", "owners": [17], "pid": {"revision_id": 0, "type": "depid", "value": "2002875"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:02002875", "sets": ["1653611787117"]}, "author_link": [], "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "246", "bibliographicPageStart": "230", "bibliographicVolumeNumber": "84", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "This study determined prognostic factors by comparing clinico-bacterial factors based on significant elevated serum procalcitonin levels in patients with suspected bloodstream infection (BSI). We retrospectively analyzed the medical records of 1,052 patients (age ≥16 years) with fever (temperature ≥38°C) and serum procalcitonin levels of ≥2.0 ng/mL, and blood culture results. The optimal cutoff value of the significant elevation of procalcitonin was determined using the minimum P-value approach. Clinico-bacterial factors were analyzed per the procalcitonin levels, and significant independent factors for short-term survival were investigated in 445 patients with BSI. Patients with suspected BSI were aged, on average, 72.3 ±15.1 years, and the incidence of positive blood culture was 42.3%; and the 14-day survival was 83.4%. Procalcitonin ≥100 ng/mL was the most significant predictor for survival. Multivariate analysis in patients with suspected BSI showed that estimated glomerular filtration rate (eGFR) \u003c30 mL/min/1.73 m^2 and procalcitonin ≥100 ng/mL were significant independent unfavorable prognostic factors. Microorganisms were similar between patients with procalcitonin level 2–99 ng/mL (n=359) and those with ≥100 ng/mL (n=86). Multivariate analysis in patients with BSI showed that eGFR \u003c30 mL/min/1.73 m^2, procalcitonin ≥100 ng/mL, and primary infectious foci were significant independent prognostic factors. Patients with foci in the gastrointestinal tract and respiratory system had unfavorable 14-day survival. In conclusions, eGFR \u003c30 mL/min/1.73 m^2 and procalcitonin ≥100 ng/mL were significant independent unfavorable prognostic factors for suspected BSI. Primary infectious foci (gastrointestinal tract and respiratory system) were associated with unfavorable short-term survival in patients with positive blood culture.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.84.2.230", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University Graduate School of Medicine, School of Medicine", "subitem_publisher_language": "en"}]}, "item_9_relation_43": {"attribute_name": "関連情報", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/842.html", "subitem_relation_type_select": "URI"}}]}, "item_9_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International", "subitem_rights_language": "en", "subitem_rights_resource": "http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_9_source_id_7": {"attribute_name": "収録物識別子", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "PISSN"}, {"subitem_source_identifier": "2186-3326", "subitem_source_identifier_type": "EISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Osamura, Yoko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nishiyama, Hideki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hattori, Takuya", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Gunji, Masaharu", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yuasa, Norihiro", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2022-05-27"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "03_Osamura.pdf", "filesize": [{"value": "2.8 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_5", "mimetype": "application/pdf", "size": 2800000.0, "url": {"objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/2002875/files/03_Osamura.pdf"}, "version_id": "effa7d14-8d13-46a8-80da-4b487a89cfa3"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "procalcitonin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "bloodstream infection", "subitem_subject_scheme": "Other"}, {"subitem_subject": "survival", "subitem_subject_scheme": "Other"}, {"subitem_subject": "renal function", "subitem_subject_scheme": "Other"}, {"subitem_subject": "blood culture", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels", "subitem_title_language": "en"}]}, "item_type_id": "40001", "owner": "17", "path": ["1653611787117"], "permalink_uri": "https://doi.org/10.18999/nagjms.84.2.230", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2022-05-27"}, "publish_date": "2022-05-27", "publish_status": "0", "recid": "2002875", "relation": {}, "relation_version_is_last": true, "title": ["Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels"], "weko_shared_id": -1}
Clinico-bacterial and prognostic factors in patients with suspected blood stream infection and elevated serum procalcitonin levels
https://doi.org/10.18999/nagjms.84.2.230
https://doi.org/10.18999/nagjms.84.2.230