| Item type |
itemtype_ver1(1) |
| 公開日 |
2023-04-25 |
| タイトル |
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|
タイトル |
トレーニング効果の生化学的評価 : multiple euglycemic clamp法を用いて |
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言語 |
ja |
| その他のタイトル |
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その他のタイトル |
Biochemical estimation of physical training effects using the multiple euglycemic clamp technique |
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言語 |
en |
| 著者 |
佐藤, 祐造
押田, 芳治
大沢, 功
佐藤, 寿一
山之内. 国男
樋口, 満
小林, 修平
篠田, 廣
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 内容記述 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Previous studies have shown that physical training improves carbohydrate metabolism. The purpose of this study was to evaluate the effects of physical training on the insulin action using the euglycemic clamp technique. The rate of insulin-mediated glucose uptake (glucose metabolism, GM) in 16 simple obese subjects (3.7±0.5mg/kg/min) and 18 obese diabetics (3.3±0.3mg/kg/min) were significantly (P<0.001) lower than those in 32 healthy controls (7.3±0.2mg/kg/min), whose values were, on the other hand, significantly (P<0.001) lower than those in 22 athletes (10.5±0.5mg/kg/min). GM in the 9 aged subjects (6.7±0.8mg/kg/min) was lower than that in young controls. In the glucose metabolic clearance rate (MCR), which was measured because of different fasting plasma glucose concentrations, the same significant changes were found in above these subjects. A positive correlation was observed between GM and V02max, while a strong inverse correlation existed between GM and BMI (r=0.841, P<0.001). MCR during regular-dose clamp in 10 young athletes (12.8±1.0ml/kg/min) was significantly higher (P<0.05) than those in 10 young untrained controls (9.0±0.7ml/kg/min), 13 aged untrained subjects (6.7±0.9ml/kg/min) and 10 aged trained athletes. MCR in aged athletes was significantly higher than that in aged untrained subjects. MCR during high-dose clamp in 10 aged untrained subjects (11.2±1.2ml/kg/min) was significantly lower (P<0.05) than those in 5 young untrained controls (17.8±1.7ml/kg/min), 5 young trained athletes (16.2±0.8ml/kg/min) and 5 aged trained athletes (18.5±l.2ml/kg/min). However no significant correlation could be observed between the latter 3 groups. These results might suggest that (1) the euglycemic clamp procedure provides a reliable estimate for training effects, and (2) physical training increases insulin sensitivity in young trained athletes and insulin responsiveness in aged athletes. |
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言語 |
en |
| 出版者 |
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|
出版者 |
名古屋大学総合保健体育科学センター |
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言語 |
ja |
| 出版者 |
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出版者 |
The Research Center of Health, Physical Fitness and Sports, Nagoya University |
|
言語 |
en |
| 言語 |
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|
言語 |
jpn |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| ID登録 |
|
|
ID登録 |
10.18999/njhpfs.14.1.9 |
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ID登録タイプ |
JaLC |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0289-5412 |
| 書誌情報 |
ja : 総合保健体育科学
en : Nagoya Journal of Health, Physical Fitness & Sports
巻 14,
号 1,
p. 9-14,
発行日 1991-03-26
|
njhpfs_14_1_9.pdf (3 MB)
