WEKO3
アイテム
{"_buckets": {"deposit": "1ec3b539-2e53-4ce5-8803-465783897dc9"}, "_deposit": {"id": "22965", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22965"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00022965", "sets": ["322"]}, "author_link": ["67772", "67773", "67774", "67775"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-02-29", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "1148", "bibliographicPageStart": "1141", "bibliographicVolumeNumber": "80", "bibliographic_titles": [{"bibliographic_title": "Bioscience, Biotechnology, and Biochemistry", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Siglecs recognize the sialic acid moiety and regulate various immune responses. In the present study, we compared the expression levels of Siglecs in human monocytes and macrophages using a quantitative real-time reverse transcription–polymerase chain reaction analysis. The differentiation of monocytes into macrophages by macrophage colony-stimulating factor or granulocyte macrophage colony-stimulating factor enhanced the expression of Siglec-7 and Siglec-9. The differentiated macrophages were stimulated by lipopolysaccharide (LPS) plus interferon (IFN)-γ or interleukin (IL)-4. The expression of Siglec-10 was enhanced by IL-4, whereas that of Siglec-7 was reduced by LPS plus IFN-γ. The expression of Siglec-9 was not affected by these stimuli. The knockdown of Siglec-9 enhanced the expression of CCR7 induced by the LPS or the LPS plus IFN-γ stimulation, and decreased the IL-4-induced expression of CD200R. These results suggest that Siglec-9 is one of the main Siglecs in human blood monocytes/macrophages and modulates innate immunity.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1080/09168451.2016.1146070"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/25146"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Taylor \u0026 Francis", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1080/09168451.2016.1146070", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "(c)日本農芸化学会. This is an Accepted Manuscript of an article published by Taylor \u0026 Francis Group in Bioscience, Biotechnology, and Biochemistry on 29/02/2016, available online: http://www.tandfonline.com/10.1080/09168451.2016.1146070.", "subitem_rights_language": "ja"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0916-8451", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Higuchi, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67772", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shoji, Toru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67773", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Iijima, Shinji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67774", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishijima, Ken-ichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67775", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-03-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Higuchi_et_al.pdf", "filesize": [{"value": "2.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 2100000.0, "url": {"label": "Higuchi_et_al.pdf ファイル公開:2017/03/01", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/22965/files/Higuchi_et_al.pdf"}, "version_id": "9fa0c85f-c66c-4beb-995b-b6f441a9078f"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "human", "subitem_subject_scheme": "Other"}, {"subitem_subject": "lectin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "macrophages", "subitem_subject_scheme": "Other"}, {"subitem_subject": "sialic acid", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Siglec", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["322"], "permalink_uri": "http://hdl.handle.net/2237/25146", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2016-12-05"}, "publish_date": "2016-12-05", "publish_status": "0", "recid": "22965", "relation": {}, "relation_version_is_last": true, "title": ["Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages"], "weko_shared_id": -1}
Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages
http://hdl.handle.net/2237/25146
http://hdl.handle.net/2237/25146b2f9e98c-a04c-448d-9c21-bdd79ac3c8a2
名前 / ファイル | ライセンス | アクション |
---|---|---|
Higuchi_et_al.pdf ファイル公開:2017/03/01 (2.1 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2016-12-05 | |||||
タイトル | ||||||
タイトル | Constitutively expressed Siglec-9 inhibits LPS-induced CCR7, but enhances IL-4-induced CD200R expression in human macrophages | |||||
言語 | en | |||||
著者 |
Higuchi, Hiroshi
× Higuchi, Hiroshi× Shoji, Toru× Iijima, Shinji× Nishijima, Ken-ichi |
|||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | ja | |||||
権利情報 | (c)日本農芸化学会. This is an Accepted Manuscript of an article published by Taylor & Francis Group in Bioscience, Biotechnology, and Biochemistry on 29/02/2016, available online: http://www.tandfonline.com/10.1080/09168451.2016.1146070. | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | human | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | lectin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | macrophages | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | sialic acid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Siglec | |||||
抄録 | ||||||
内容記述 | Siglecs recognize the sialic acid moiety and regulate various immune responses. In the present study, we compared the expression levels of Siglecs in human monocytes and macrophages using a quantitative real-time reverse transcription–polymerase chain reaction analysis. The differentiation of monocytes into macrophages by macrophage colony-stimulating factor or granulocyte macrophage colony-stimulating factor enhanced the expression of Siglec-7 and Siglec-9. The differentiated macrophages were stimulated by lipopolysaccharide (LPS) plus interferon (IFN)-γ or interleukin (IL)-4. The expression of Siglec-10 was enhanced by IL-4, whereas that of Siglec-7 was reduced by LPS plus IFN-γ. The expression of Siglec-9 was not affected by these stimuli. The knockdown of Siglec-9 enhanced the expression of CCR7 induced by the LPS or the LPS plus IFN-γ stimulation, and decreased the IL-4-induced expression of CD200R. These results suggest that Siglec-9 is one of the main Siglecs in human blood monocytes/macrophages and modulates innate immunity. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Taylor & Francis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1080/09168451.2016.1146070 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0916-8451 | |||||
書誌情報 |
en : Bioscience, Biotechnology, and Biochemistry 巻 80, 号 6, p. 1141-1148, 発行日 2016-02-29 |
|||||
著者版フラグ | ||||||
値 | author | |||||
URI | ||||||
識別子 | http://doi.org/10.1080/09168451.2016.1146070 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/25146 | |||||
識別子タイプ | HDL |