{"_buckets": {"deposit": "1e181d40-8c36-4929-975d-683de5aa010a"}, "_deposit": {"id": "22974", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22974"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00022974"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "348", "bibliographicPageStart": "343", "bibliographicVolumeNumber": "478", "bibliographic_titles": [{"bibliographic_title": "Biochemical and Biophysical Research Communications"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Transglutaminase (TGase) catalyzes protein cross-linking reactions essential for several biological processes. In differentiating keratinocytes, TG1 (keratinocyte-type) is crucial for the cross-linking of substrate proteins required for the complete formation of the cornified envelop, a proteinaceous supermolecule located in the outermost layer of the epidermis. TG1 expressions and its substrate were induced in cultured keratinocytes at differentiation-stage specific manner. In the cultured keratinocytes, we used the TG1-specific substrate peptide, which enables the specific detection of enzymatic activity to investigate its induction patterns. As a further application of the substrate peptide, several substrate candidates of TG1 that may be essential for cornified envelope formation were identified and characterized.", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://dx.doi.org/10.1016/j.bbrc.2016.07.051"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/25155"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\u00a9 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0006-291X", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamane, Miki"}], "nameIdentifiers": [{"nameIdentifier": "67840", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugimura, Kayoko"}], "nameIdentifiers": [{"nameIdentifier": "67841", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawasaki, Hiroko"}], "nameIdentifiers": [{"nameIdentifier": "67842", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tatsukawa, Hideki"}], "nameIdentifiers": [{"nameIdentifier": "67843", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hitomi, Kiyotaka"}], "nameIdentifiers": [{"nameIdentifier": "67844", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-09-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BBRC-S-16-06867_Redacted.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "BBRC-S-16-06867_Redacted.pdf \u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2017/09/01", "url": "https://nagoya.repo.nii.ac.jp/record/22974/files/BBRC-S-16-06867_Redacted.pdf"}, "version_id": "6f4793b7-9038-4127-a2e9-fc6c00779e36"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Transglutaminase", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Keratinocyte", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Epidermis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes"}]}, "item_type_id": "10", "owner": "1", "path": ["1903/1904/1905"], "permalink_uri": "http://hdl.handle.net/2237/25155", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-12-07"}, "publish_date": "2016-12-07", "publish_status": "0", "recid": "22974", "relation": {}, "relation_version_is_last": true, "title": ["Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes"], "weko_shared_id": null}