WEKO3
アイテム
{"_buckets": {"deposit": "1e181d40-8c36-4929-975d-683de5aa010a"}, "_deposit": {"id": "22974", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22974"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00022974", "sets": ["1905"]}, "author_link": ["67840", "67841", "67842", "67843", "67844"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "348", "bibliographicPageStart": "343", "bibliographicVolumeNumber": "478", "bibliographic_titles": [{"bibliographic_title": "Biochemical and Biophysical Research Communications", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Transglutaminase (TGase) catalyzes protein cross-linking reactions essential for several biological processes. In differentiating keratinocytes, TG1 (keratinocyte-type) is crucial for the cross-linking of substrate proteins required for the complete formation of the cornified envelop, a proteinaceous supermolecule located in the outermost layer of the epidermis. TG1 expressions and its substrate were induced in cultured keratinocytes at differentiation-stage specific manner. In the cultured keratinocytes, we used the TG1-specific substrate peptide, which enables the specific detection of enzymatic activity to investigate its induction patterns. As a further application of the substrate peptide, several substrate candidates of TG1 that may be essential for cornified envelope formation were identified and characterized.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://dx.doi.org/10.1016/j.bbrc.2016.07.051"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/25155"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.bbrc.2016.07.051", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0006-291X", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamane, Miki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67840", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugimura, Kayoko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67841", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawasaki, Hiroko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67842", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tatsukawa, Hideki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67843", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hitomi, Kiyotaka", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67844", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-09-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BBRC-S-16-06867_Redacted.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "BBRC-S-16-06867_Redacted.pdf ファイル公開:2017/09/01", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/22974/files/BBRC-S-16-06867_Redacted.pdf"}, "version_id": "6f4793b7-9038-4127-a2e9-fc6c00779e36"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Transglutaminase", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Keratinocyte", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Epidermis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["1905"], "permalink_uri": "http://hdl.handle.net/2237/25155", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2016-12-07"}, "publish_date": "2016-12-07", "publish_status": "0", "recid": "22974", "relation": {}, "relation_version_is_last": true, "title": ["Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes"], "weko_shared_id": -1}
Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes
http://hdl.handle.net/2237/25155
http://hdl.handle.net/2237/251558a04c0d8-cdbd-42ad-80de-4d4cf0f13f27
名前 / ファイル | ライセンス | アクション |
---|---|---|
BBRC-S-16-06867_Redacted.pdf ファイル公開:2017/09/01 (1.3 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2016-12-07 | |||||
タイトル | ||||||
タイトル | Analysis on transglutaminase 1 and its substrates using specific substrate peptide in cultured keratinocytes | |||||
言語 | en | |||||
著者 |
Yamane, Miki
× Yamane, Miki× Sugimura, Kayoko× Kawasaki, Hiroko× Tatsukawa, Hideki× Hitomi, Kiyotaka |
|||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Transglutaminase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Keratinocyte | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epidermis | |||||
抄録 | ||||||
内容記述 | Transglutaminase (TGase) catalyzes protein cross-linking reactions essential for several biological processes. In differentiating keratinocytes, TG1 (keratinocyte-type) is crucial for the cross-linking of substrate proteins required for the complete formation of the cornified envelop, a proteinaceous supermolecule located in the outermost layer of the epidermis. TG1 expressions and its substrate were induced in cultured keratinocytes at differentiation-stage specific manner. In the cultured keratinocytes, we used the TG1-specific substrate peptide, which enables the specific detection of enzymatic activity to investigate its induction patterns. As a further application of the substrate peptide, several substrate candidates of TG1 that may be essential for cornified envelope formation were identified and characterized. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.bbrc.2016.07.051 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0006-291X | |||||
書誌情報 |
en : Biochemical and Biophysical Research Communications 巻 478, 号 1, p. 343-348, 発行日 2016-09 |
|||||
著者版フラグ | ||||||
値 | author | |||||
URI | ||||||
識別子 | http://dx.doi.org/10.1016/j.bbrc.2016.07.051 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/25155 | |||||
識別子タイプ | HDL |