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Characterization of chicken interferon-inducible transmembrane protein-10
http://hdl.handle.net/2237/26836
http://hdl.handle.net/2237/26836c5a054fc-fd9d-4468-be7d-dbe217b6de29
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Graphical-Abst.pdf ファイル公開：2018/01/13 (67.4 kB)
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Okuzaki-Figs.pdf ファイル公開：2018/01/13 (2.3 MB)
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Okuzaki-text.pdf ファイル公開：2018/01/13 (230.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-25 | |||||
| タイトル | ||||||
| タイトル | Characterization of chicken interferon-inducible transmembrane protein-10 | |||||
| 言語 | en | |||||
| 著者 |
Okuzaki, Yuya
× Okuzaki, Yuya× Kidani, Shunsuke× Kaneoka, Hidenori× Iijima, Shinji× Nishijima, Ken-ichi |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | (c)日本農芸化学会. This is an Accepted Manuscript of an article published by Taylor & Francis Group in Bioscience, Biotechnology, and Biochemistry on 13/01/2017, available online: http://dx.doi.org/10.1080/09168451.2016.1274639 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | chicken | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | interferon-inducible transmembrane protein 10 (IFITM10) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | interferon | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | virus prevention | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Interferon-inducible transmembrane protein (IFITM) family proteins are antivirus factors. In the present study, we examined the expression pattern of chicken IFITM10 using quantitative reverse transcription-polymerase chain reaction. In adult chickens, IFITM10 levels were markedly lower than those of IFITM3, which exhibits antivirus activity. On the other hand, IFITM10 was expressed in levels similar to those of IFITM3 in embryonic organs. Primordial germ cells in 2.5-d embryos expressed high levels of IFITM10, which gradually decreased with time. The interferon-α stimulation of embryonic fibroblast cells did not enhance the expression of IFITM10. The forced expression of IFITM10 slightly inhibited the infectivity of the VSV-G-pseudotyped lentiviral vector. Furthermore, cell fusion was inhibited by IFITM10 when HeLa cells transfected with the VSV-G expression vector were treated with low pH buffer. Although it remains unclear whether IFITM10 inhibits viral infections under physiological conditions, these results suggest that chicken IFITM10 exhibits antivirus activity. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Taylor & Francis | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1080/09168451.2016.1274639 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0916-8451 | |||||
| 書誌情報 |
en : Bioscience, Biotechnology, and Biochemistry 巻 81, 号 5, p. 914-921, 発行日 2017-01-13 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
| URI | ||||||
| 識別子 | http://dx.doi.org/10.1080/09168451.2016.1274639 | |||||
| 識別子タイプ | DOI | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/26836 | |||||
| 識別子タイプ | HDL | |||||
