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  1. B300 農学部/生命農学研究科
  2. B300a 雑誌掲載論文
  3. 学術雑誌

Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae

http://hdl.handle.net/2237/26857
http://hdl.handle.net/2237/26857
0206937c-296b-4e3b-a001-766fd4e6d4c9
名前 / ファイル ライセンス アクション
manuscript.pdf manuscript.pdf ファイル公開:2018/06/03 (1.9 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-08-01
タイトル
タイトル Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae
言語 en
著者 Hayakawa, Hajime

× Hayakawa, Hajime

WEKO 72934

en Hayakawa, Hajime

Search repository
Sobue, Fumiaki

× Sobue, Fumiaki

WEKO 72935

en Sobue, Fumiaki

Search repository
Motoyama, Kento

× Motoyama, Kento

WEKO 72936

en Motoyama, Kento

Search repository
Yoshimura, Tohru

× Yoshimura, Tohru

WEKO 72937

en Yoshimura, Tohru

Search repository
Hemmi, Hisashi

× Hemmi, Hisashi

WEKO 72938

en Hemmi, Hisashi

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
キーワード
主題Scheme Other
主題 Mevalonate pathway
キーワード
主題Scheme Other
主題 isoprenoid
キーワード
主題Scheme Other
主題 mevalonate kinase
キーワード
主題Scheme Other
主題 phosphomevalonate kinase
キーワード
主題Scheme Other
主題 diphosphomevalonate decarboxylase
抄録
内容記述 The mevalonate pathway is prevalent in eukaryotes, archaea, and a limited number of bacteria. This pathway yields the fundamental precursors for isoprenoid biosynthesis, i.e., isopentenyl diphosphate and dimethylally diphosphate. In the downstream part of the general eukaryote-type mevalonate pathway,mevalonate is converted into isopentenyl diphosphate by the sequential actions of mevalonate kinase, phosphomevalonate kinase, and diphosphomevalonte decarboxylase, while a partial lack of the putative genes of these enzymes is sometimes observed in archaeal and bacterial genomes. The absence of these genes has led to the recent discovery of modified mevalonate pathways. Therefore, we decided to investigate the mevalonate pathway of Flavobacterium johnsoniae, a bacterium of the phylum Bacteroidetes,which is reported to lack the genes of mevalonate kinase and phosphomevalonate kinase. This study provides proof of the existence of the general mevalonate pathway in F. johnsoniae, although the pathway involves the kinases that are distantly related to the known enzymes.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.bbrc.2017.04.120
ISSN
収録物識別子タイプ PISSN
収録物識別子 0006-291X
書誌情報 en : Biochemical and Biophysical Research Communications

巻 487, 号 3, p. 702-708, 発行日 2017-06-03
著者版フラグ
値 author
URI
識別子 https://doi.org/10.1016/j.bbrc.2017.04.120
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/26857
識別子タイプ HDL
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