{"_buckets": {"deposit": "52902a88-0017-42e5-afe1-c819de929bf9"}, "_deposit": {"id": "24656", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "24656"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00024656"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "1495", "bibliographicPageStart": "1487", "bibliographicVolumeNumber": "45", "bibliographic_titles": [{"bibliographic_title": "Annals of Biomedical Engineering"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A novel apparatus for the multifaceted evaluation of artery function was developed. It measures endothelial and smooth muscle functions and the pressure\u2013strain elastic modulus (Ep). A rigid airtight chamber with an ultrasound probe was attached to the upper arm to manipulate the transmural pressure of the brachial artery. Endothelial function was measured via a standard flow-mediated dilation (FMD) protocol. Smooth muscle function was evaluated via a myogenic contraction of the artery following the application of negative pressure to the chamber and was named pressure-mediated contraction (PMC). Ep was obtained by measuring the instantaneous increase in the artery diameter following the negative pressure application. The PMC and FMD values had a significant negative correlation with age, indicating that the age-related decrease in FMD is caused by the decay of endothelial and smooth muscle function. A consideration of PMC may help improve the accuracy of artery function measurement. Ep in subjects aged \u003e40 years was found to be significantly higher in the supra-physiological pressure range than in the physiological one (p = 0.02); this did not occur in younger subjects. Artery stiffening may begin in the supra-physiological range, and this stiffness may also be used for the diagnosis of atherosclerosis.", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "https://doi.org/10.1007/s10439-017-1810-z"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/26875"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Springer"}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "The final publication is available at Springer via https://doi.org/10.1007/s10439-017-1810-z"}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0090-6964", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yaguchi, Toshiyuki"}], "nameIdentifiers": [{"nameIdentifier": "73058", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Cong, Yalin"}], "nameIdentifiers": [{"nameIdentifier": "73059", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimo, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "73060", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurokawa, Takahiro"}], "nameIdentifiers": [{"nameIdentifier": "73061", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugita, Shukei"}], "nameIdentifiers": [{"nameIdentifier": "73062", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagayama, Kazuaki"}], "nameIdentifiers": [{"nameIdentifier": "73063", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Masuda, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "73064", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Takeo"}], "nameIdentifiers": [{"nameIdentifier": "73065", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-06-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Paper49forRepository.pdf", "filesize": [{"value": "8.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 8500000.0, "url": {"label": "Paper49forRepository.pdf \u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2018/06/01", "url": "https://nagoya.repo.nii.ac.jp/record/24656/files/Paper49forRepository.pdf"}, "version_id": "9c5b6dbb-fc89-491f-8c83-1ad27491fffa"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A Novel Apparatus for the Multifaceted Evaluation of Arterial Function Through Transmural Pressure Manipulation", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "A Novel Apparatus for the Multifaceted Evaluation of Arterial Function Through Transmural Pressure Manipulation"}]}, "item_type_id": "10", "owner": "1", "path": ["320/321/322"], "permalink_uri": "http://hdl.handle.net/2237/26875", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2017-08-03"}, "publish_date": "2017-08-03", "publish_status": "0", "recid": "24656", "relation": {}, "relation_version_is_last": true, "title": ["A Novel Apparatus for the Multifaceted Evaluation of Arterial Function Through Transmural Pressure Manipulation"], "weko_shared_id": null}