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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 79(3)

Optimized treatment strategy of radiotherapy for early glottic squamous cell carcinomas : An initial analysis

https://doi.org/10.18999/nagjms.79.3.331
https://doi.org/10.18999/nagjms.79.3.331
7956889f-3165-4039-8f93-3f2a11661dc2
名前 / ファイル ライセンス アクション
06_Kimura.pdf 06_Kimura.pdf (293.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-08-23
タイトル
タイトル Optimized treatment strategy of radiotherapy for early glottic squamous cell carcinomas : An initial analysis
著者 Kimura, Kana

× Kimura, Kana

WEKO 73222

Kimura, Kana

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Itoh, Yoshiyuki

× Itoh, Yoshiyuki

WEKO 73223

Itoh, Yoshiyuki

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Okada, Tohru

× Okada, Tohru

WEKO 73224

Okada, Tohru

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Kubota, Seiji

× Kubota, Seiji

WEKO 73225

Kubota, Seiji

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Kawamura, Mariko

× Kawamura, Mariko

WEKO 73226

Kawamura, Mariko

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Nakahara, Rie

× Nakahara, Rie

WEKO 73227

Nakahara, Rie

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Oie, Yumi

× Oie, Yumi

WEKO 73228

Oie, Yumi

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Kozai, Yuka

× Kozai, Yuka

WEKO 73229

Kozai, Yuka

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Takase, Yuuki

× Takase, Yuuki

WEKO 73230

Takase, Yuuki

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Tsuzuki, Hidenori

× Tsuzuki, Hidenori

WEKO 73231

Tsuzuki, Hidenori

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Nishio, Naoki

× Nishio, Naoki

WEKO 73232

Nishio, Naoki

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Hiramatsu, Mariko

× Hiramatsu, Mariko

WEKO 73233

Hiramatsu, Mariko

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Fujimoto, Yasushi

× Fujimoto, Yasushi

WEKO 73234

Fujimoto, Yasushi

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Mizutani, Takefumi

× Mizutani, Takefumi

WEKO 73235

Mizutani, Takefumi

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Naganawa, Shinji

× Naganawa, Shinji

WEKO 73236

Naganawa, Shinji

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キーワード
主題Scheme Other
主題 early glottic cancer
キーワード
主題Scheme Other
主題 radiotherapy
キーワード
主題Scheme Other
主題 chemoradiotherapy
抄録
内容記述 The purpose of this study was to evaluate the clinical outcomes of radiotherapy for patients with T1/T2 glottic carcinoma. Patients with T1/T2 glottic carcinoma histopathologically diagnosed with squamous cell carcinoma and treated at our hospital between 2007 and 2015 were analyzed retrospectively. Our strategy for T1/T2 glottic carcinoma was as follows: radiotherapy alone with 2.25 Gy per fraction to a total of 25–28 fractions for patients with non-bulky T1 glottic carcinoma; concurrent chemoradiotherapy with oral S-1 and radiotherapy with 2 Gy per fraction to a total of 30 fractions for patients with T1 bulky/T2 favorable glottic carcinoma; or chemoradiotherapy with high-dose cisplatin and radiotherapy with 2 Gy per fraction to a total of 35 fractions for T2 unfavorable glottic carcinoma. Forty-eight patients were eligible. The median follow-up period among surviving patients was 38 months (range, 11–107). The disease was T1a in 23%, T1b in 13%, and T2 in 65% of patients. The 3-year local control rate in all patients, T1a, T1b, and T2 was 96.7%, 100%, 100%, and 96.0%, respectively. Of the 46 patients, one with T2 glottic carcinoma developed recurrent disease at the primary site, and one with T2 glottic carcinoma had lymph node recurrences in the neck. Acute Grade 3 dermatitis occurred in 8 (17%) patients and late Grade 2 hypothyroidism occurred in 2 (4%) patients. This retrospective study shows that our optimized treatment strategy of radiotherapy depending on the stage of early glottic carcinoma is not only effective but also well-tolerated.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.79.3.331
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 79, 号 3, p. 331-338, 発行日 2017-08
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/793.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/26911
識別子タイプ HDL
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