{"_buckets": {"deposit": "bc542424-7439-4bbe-a479-fec39732d401"}, "_deposit": {"id": "25137", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25137"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00025137", "sets": ["696"]}, "author_link": ["75012", "75013", "75014", "75015", "75016"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-09-29", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "9062", "bibliographicPageStart": "9058", "bibliographicVolumeNumber": "2", "bibliographic_titles": [{"bibliographic_title": "ChemistrySelect", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Inhibition self-assembly of β-amyloid (Aβ) is considered to be a strategy that can be potentially useful to develop treatment for Alzheimer\u0027s disease (AD). We have discovered that a protein unit that is found in the fimbriae of Gram-negative bacteria, which has a vacant site for a β-sheet strand, prevents Aβ oligomerization effectively. Moreover, we found that a soluble but denatured form of this protein shows even higher potency. Our results also demonstrate the applicability of denatured proteins as pharmaceutical material.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1002/slct.201700658"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/27357"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Wiley", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1002/slct.201700658", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This is the peer reviewed version of the following article: [K. Yamamoto, M. Oyaizu, T. Takahashi, Y. Watanabe, O. Shoji.(2017), Inhibiting Aggregation of β-Amyloid by Folded and Unfolded Forms of Fimbrial Protein of Gram-Negative Bacteria.　ChemistrySelect,2:9058–9062. doi:10.1002/slct.201700658], which has been published in final form at [http://doi.org/10.1002/slct.201700658]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2365-6549", "subitem_source_identifier_type": "EISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamamoto, Keisuke", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75012", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oyaizu, Misa", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75013", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takahashi, Tsuyoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75014", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Watanabe, Yoshihito", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75015", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shoji, Osami", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75016", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-09-29"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "manuscript_slct_201700658R2.pdf", "filesize": [{"value": "1.6 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 1600000.0, "url": {"label": "manuscript_slct_201700658R2.pdf ファイル公開日:2018/09/29", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/25137/files/manuscript_slct_201700658R2.pdf"}, "version_id": "0aad957f-430a-4c2b-87fb-184d9c89160f"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Inhibiting Aggregation of β-Amyloid by Folded and Unfolded Forms of Fimbrial Protein of Gram-Negative Bacteria", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Inhibiting Aggregation of β-Amyloid by Folded and Unfolded Forms of Fimbrial Protein of Gram-Negative Bacteria", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["696"], "permalink_uri": "http://hdl.handle.net/2237/27357", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-02-05"}, "publish_date": "2018-02-05", "publish_status": "0", "recid": "25137", "relation": {}, "relation_version_is_last": true, "title": ["Inhibiting Aggregation of β-Amyloid by Folded and Unfolded Forms of Fimbrial Protein of Gram-Negative Bacteria"], "weko_shared_id": -1}