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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 80(3)

Primary hepatic carcinosarcoma with multimodal treatment

https://doi.org/10.18999/nagjms.80.3.423
https://doi.org/10.18999/nagjms.80.3.423
81c6d536-a948-4a61-a626-403a9464f06d
名前 / ファイル ライセンス アクション
15_Kurita.pdf 15_Kurita.pdf (3.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2018-09-05
タイトル
タイトル Primary hepatic carcinosarcoma with multimodal treatment
著者 Kurita, Daisuke

× Kurita, Daisuke

WEKO 85095

Kurita, Daisuke

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Mokuno, Yasuji

× Mokuno, Yasuji

WEKO 85096

Mokuno, Yasuji

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Matsubara, Hideo

× Matsubara, Hideo

WEKO 85097

Matsubara, Hideo

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Kaneko, Hirokazu

× Kaneko, Hirokazu

WEKO 85098

Kaneko, Hirokazu

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Shamoto, Mikihiro

× Shamoto, Mikihiro

WEKO 85099

Shamoto, Mikihiro

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Satou, Akira

× Satou, Akira

WEKO 85100

Satou, Akira

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Iyomasa, Shinsuke

× Iyomasa, Shinsuke

WEKO 85101

Iyomasa, Shinsuke

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キーワード
主題Scheme Other
主題 hepatic carcinosarcoma
キーワード
主題Scheme Other
主題 chemoradiotherapy
キーワード
主題Scheme Other
主題 doxorubicin
キーワード
主題Scheme Other
主題 ifosfamide
抄録
内容記述 Hepatic carcinosarcoma (HCS) generally presents in advanced stages, demonstrates aggressive behavior, and has a poor prognosis. Other than curative primary resection, no effective treatment options exist. We present a case of resected HCS with four repeat resections for solitary lymph node recurrence followed by chemoradiotherapy with doxorubicin and ifosfamide. A 67-year-old Japanese man was admitted to our hospital for evaluation of an asymptomatic hepatic tumor. The patient underwent right hepatectomy with a presumptive preoperative diagnosis of atypical hepatocellular carcinoma. Based on histopathological and immunohistochemical findings, the tumor was diagnosed as HCS containing osteosarcoma and chondrosarcoma components. After the initial surgery, the patient underwent four additional resections for solitary lymph node HCS recurrence, and then underwent chemoradiotherapy with doxorubicin and ifosfamide for an unresectable lymph node recurrence. Chemotherapy was stopped after two cycles because of severe adverse events, although chemoradiotherapy markedly reduced the size of the lymph node recurrence and provided a progression-free survival of 12 months. Thirty-seven months after the initial surgery, the patient died of cardiac invasion of multiple mediastinal lymph node metastases. The clinical course outlined in this case report suggests that chemoradiotherapy with doxorubicin and ifosfamide for metastatic HCS may prolong survival in patients with unresectable lesions.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.80.3.423
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/803.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 80, 号 3, p. 423-429, 発行日 2018-08
著者版フラグ
値 publisher
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