{"_buckets": {"deposit": "60aabe3f-c579-4ef8-8793-1d0a0e5a7eeb"}, "_deposit": {"id": "26361", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "26361"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00026361"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "361", "bibliographicPageStart": "357", "bibliographicVolumeNumber": "67", "bibliographic_titles": [{"bibliographic_title": "Parasitology International"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Hymenolepis diminuta is a parasitic tapeworm of the rat small intestine and is recognized as a useful model for the analysis of cestode-host interactions. In this study, we analyzed factors affecting the biomass of the tapeworm through use of rat strains carrying genetic mutations, namely X-linked severe combined immunodeficiency (xscid; T, B and NK cells deficiency), nude (rnu; T cell deficiency), and mast cell deficient rats. The worm biomass of F344-xscid rats after infection with 5 cysticercoids was much larger than control F344 rats from 3 to 8\u202fweeks. The biomass of F344-rnu rats was also larger than the controls, but was intermediate between F344-xscid and control rats. These observations demonstrated that host immunity can control the maximal tapeworm biomass, i.e., carrying capacity, of the rat small intestine. Both T cell and other immune cells (B and NK cells) have roles in determining the carrying capacity of tapeworms. Total worm biomass and worm numbers in mast cell deficient rats (WsRC-Ws/Ws) were not significantly different from control WsRC-+/+ rats after 3 and 6\u202fweeks of primary infection. Mast cell deficient rats displayed reinfection resistance for worm biomass but not worm expulsion. These findings suggest that the mast cell has a role for controlling the biomass of this tapeworm in reinfection alone, but does not affect the rate of worm expulsion. Overall, our findings indicate that the mast cell is not a major effector cell for the control of the carrying capacity of tapeworms. The identity of the major effector cell remains unknown.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2019-08-01", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.parint.2018.02.003", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\u00a9 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "1383-5769", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ohno, Tamio"}], "nameIdentifiers": [{"nameIdentifier": "85258", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kai, Takuya"}], "nameIdentifiers": [{"nameIdentifier": "85259", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyasaka, Yuki"}], "nameIdentifiers": [{"nameIdentifier": "85260", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Maruyama, Haruhiko"}], "nameIdentifiers": [{"nameIdentifier": "85261", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishih, Akira"}], "nameIdentifiers": [{"nameIdentifier": "85262", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kino, Hideto"}], "nameIdentifiers": [{"nameIdentifier": "85263", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Ohno_T_H_diminuta-Revised.pdf", "filesize": [{"value": "267.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 267200.0, "url": {"label": "Ohno_T_H_diminuta-Revised", "url": "https://nagoya.repo.nii.ac.jp/record/26361/files/Ohno_T_H_diminuta-Revised.pdf"}, "version_id": "13ba5c24-44cd-41a3-b4db-bfa193ee3e22"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Carrying capacity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Hymenolepis diminuta", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Immune-deficient rat", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mast cell deficient rat", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Worm biomass", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Intestinal immunity suppresses carrying capacity of rats for the model tapeworm, Hymenolepis diminuta", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Intestinal immunity suppresses carrying capacity of rats for the model tapeworm, Hymenolepis diminuta"}]}, "item_type_id": "10", "owner": "1", "path": ["499/500/501"], "permalink_uri": "http://hdl.handle.net/2237/00028564", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2018-09-11"}, "publish_date": "2018-09-11", "publish_status": "0", "recid": "26361", "relation": {}, "relation_version_is_last": true, "title": ["Intestinal immunity suppresses carrying capacity of rats for the model tapeworm, Hymenolepis diminuta"], "weko_shared_id": null}