{"_buckets": {"deposit": "7b0d53b6-8e5c-4ec5-bc1a-9fb51b07f962"}, "_deposit": {"id": "28628", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28628"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028628", "sets": ["501"]}, "author_link": ["93772", "93773", "93774", "93775"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "655", "bibliographicPageStart": "651", "bibliographicVolumeNumber": "29", "bibliographic_titles": [{"bibliographic_title": "Modern Rheumatology", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Objectives: Kawasaki disease (KD) is one of the most common childhood vasculitides. Some serological studies have suggested an etiological relationship between KD and human herpesvirus (HHV)-6 or HHV-7. However, primary or reactivated HHV-6 and -7 has not been fully investigated in patients with KD. Methods: Twenty-three patients with KD were prospectively enrolled in this study. Peripheral blood was collected in the acute and convalescence phases, and HHV-6 and -7 viral loads were measured by real-time PCR. Results: In the acute phase, HHV-6 and -7 DNA was detected in 7 (30%) patients each, compared to 13 (57%) and 9 (39%) patients in the convalescence phase, respectively. HHV-6 and -7 DNA loads were significantly higher in the convalescence phase than in the acute phase. Significant increases in HHV-6 and -7 DNA loads were not observed in disease control patients. Taking into account HHV-6 and -7 serostatus, reactivation of HHV-6 and -7 was observed in 7 and 9 patients, respectively. KD patients with HHV-6 reactivation showed higher C-reactive protein levels and more frequently required steroid therapies than patients without reactivation. Conclusion: HHV-6 and -7 reactivation is frequent in KD patients. HHV-6 reactivation might exacerbate the severity of KD.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "Published online: 05 Sep 2018", "subitem_description_language": "en", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Taylor \u0026 Francis", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1080/14397595.2018.1510758", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This is an Accepted Manuscript of an article published by Taylor \u0026 Francis Group in Modern Rheumatology on 05/09/2018, available online: http://www.tandfonline.com/10.1080/14397595.2018.1510758. ", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN（print）", "attribute_value_mlt": [{"subitem_source_identifier": "1439-7595", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kawano, Yoshihiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "93772", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawada, Jun-ichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "93773", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagai, Noriko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "93774", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Yoshinori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "93775", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-10-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "MR_Kawano_repository.pdf", "filesize": [{"value": "314.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 314800.0, "url": {"label": "MR_Kawano_repository", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/28628/files/MR_Kawano_repository.pdf"}, "version_id": "db737c92-52dd-4fc6-95db-3226cc7b26e7"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Human herpesvirus 6", "subitem_subject_scheme": "Other"}, {"subitem_subject": "human herpesvirus 7", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Kawasaki disease", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Reactivation of human herpesviruses 6 and 7 in Kawasaki disease", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Reactivation of human herpesviruses 6 and 7 in Kawasaki disease", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["501"], "permalink_uri": "http://hdl.handle.net/2237/00030818", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2019-10-18"}, "publish_date": "2019-10-18", "publish_status": "0", "recid": "28628", "relation": {}, "relation_version_is_last": true, "title": ["Reactivation of human herpesviruses 6 and 7 in Kawasaki disease"], "weko_shared_id": -1}