{"_buckets": {"deposit": "7b0d53b6-8e5c-4ec5-bc1a-9fb51b07f962"}, "_deposit": {"id": "28628", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28628"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028628"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "655", "bibliographicPageStart": "651", "bibliographicVolumeNumber": "29", "bibliographic_titles": [{"bibliographic_title": "Modern Rheumatology"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Objectives: Kawasaki disease (KD) is one of the most common childhood vasculitides. Some serological studies have suggested an etiological relationship between KD and human herpesvirus (HHV)-6 or HHV-7. However, primary or reactivated HHV-6 and -7 has not been fully investigated in patients with KD. Methods: Twenty-three patients with KD were prospectively enrolled in this study. Peripheral blood was collected in the acute and convalescence phases, and HHV-6 and -7 viral loads were measured by real-time PCR. Results: In the acute phase, HHV-6 and -7 DNA was detected in 7 (30%) patients each, compared to 13 (57%) and 9 (39%) patients in the convalescence phase, respectively. HHV-6 and -7 DNA loads were significantly higher in the convalescence phase than in the acute phase. Significant increases in HHV-6 and -7 DNA loads were not observed in disease control patients. Taking into account HHV-6 and -7 serostatus, reactivation of HHV-6 and -7 was observed in 7 and 9 patients, respectively. KD patients with HHV-6 reactivation showed higher C-reactive protein levels and more frequently required steroid therapies than patients without reactivation. Conclusion: HHV-6 and -7 reactivation is frequent in KD patients. HHV-6 reactivation might exacerbate the severity of KD.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "Published online: 05 Sep 2018", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Taylor \u0026 Francis"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1080/14397595.2018.1510758", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "This is an Accepted Manuscript of an article published by Taylor \u0026 Francis Group in Modern Rheumatology on 05/09/2018, available online: http://www.tandfonline.com/10.1080/14397595.2018.1510758. "}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "1439-7595", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kawano, Yoshihiko"}], "nameIdentifiers": [{"nameIdentifier": "93772", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawada, Jun-ichi"}], "nameIdentifiers": [{"nameIdentifier": "93773", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagai, Noriko"}], "nameIdentifiers": [{"nameIdentifier": "93774", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Yoshinori"}], "nameIdentifiers": [{"nameIdentifier": "93775", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-10-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "MR_Kawano_repository.pdf", "filesize": [{"value": "314.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 314800.0, "url": {"label": "MR_Kawano_repository", "url": "https://nagoya.repo.nii.ac.jp/record/28628/files/MR_Kawano_repository.pdf"}, "version_id": "db737c92-52dd-4fc6-95db-3226cc7b26e7"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Human herpesvirus 6", "subitem_subject_scheme": "Other"}, {"subitem_subject": "human herpesvirus 7", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Kawasaki disease", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Reactivation of human herpesviruses 6 and 7 in Kawasaki disease", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Reactivation of human herpesviruses 6 and 7 in Kawasaki disease"}]}, "item_type_id": "10", "owner": "1", "path": ["499/500/501"], "permalink_uri": "http://hdl.handle.net/2237/00030818", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2019-10-18"}, "publish_date": "2019-10-18", "publish_status": "0", "recid": "28628", "relation": {}, "relation_version_is_last": true, "title": ["Reactivation of human herpesviruses 6 and 7 in Kawasaki disease"], "weko_shared_id": null}