{"_buckets": {"deposit": "06f2adc2-9ff4-47d6-bab7-18c6e9095533"}, "_deposit": {"id": "28729", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28729"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028729"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageStart": "e2698", "bibliographicVolumeNumber": "34", "bibliographic_titles": [{"bibliographic_title": "Human Psychopharmacology: Clinical and Experimental"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Objective: Burning mouth syndrome (BMS) and atypical odontalgia (AO) are examples of somatic symptom disorders with predominant pain around the orofacial region. Neuroinflammation is thought to play a role in the mechanisms, but few studies have been conducted. We aimed to better understand the role of neuroinflammation in the pathophysiology and treatment of BMS/AO. Methods: Plasma levels of 28 neuroinflammation\u2010related molecules were determined in 44 controls and 48 BMS/AO patients both pretreatment and 12\u2010week post\u2010treatment with duloxetine. Results: Baseline plasma levels of interleukin (IL)\u20101\u03b2 (p \u003c .0001), IL\u20101 receptor antagonist (p \u003c .001), IL\u20106 (p \u003c .0001), macrophage inflammatory protein\u20101\u03b2 (p \u003c .0001), and platelet\u2010derived growth factor\u2010bb (.04) were significantly higher in patients than in controls. Plasma levels of granulocyte macrophage colony stimulating factor were significantly higher in patients than in controls (p \u003c .001) and decreased with treatment (.009). Plasma levels of eotaxin, monocyte chemoattractant protein\u20101, and vascular endothelial growth factor decreased significantly with treatment (p \u003c .001, .022, and .029, respectively). Conclusions: Inflammatory mechanisms may be involved in the pathophysiology and/or treatment response of somatic symptom disorders with predominant pain around the orofacial region.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2020-07-01", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Wiley"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1002/hup.2698", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\"This is the peer reviewed version of the following article: [ Miyauchi, T, Tokura, T, Kimura, H, et al. Effect of antidepressant treatment on plasma levels of neuroinflammation\u2010associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region. Hum Psychopharmacol Clin Exp. 2019; 34:e2698. https://doi.org/10.1002/hup.2698], which has been published in final form at [https://doi.org/10.1002/hup.2698]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.\""}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0885-6222", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Miyauchi, Tomoya"}], "nameIdentifiers": [{"nameIdentifier": "94353", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tokura, Tatsuya"}], "nameIdentifiers": [{"nameIdentifier": "94354", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kimura, Hiroyuki"}], "nameIdentifiers": [{"nameIdentifier": "94355", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Mikiko"}], "nameIdentifiers": [{"nameIdentifier": "94356", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umemura, Eri"}], "nameIdentifiers": [{"nameIdentifier": "94357", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato (Boku), Aiji"}], "nameIdentifiers": [{"nameIdentifier": "94358", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagashima, Wataru"}], "nameIdentifiers": [{"nameIdentifier": "94359", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tonoike, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "94360", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Yasuko"}], "nameIdentifiers": [{"nameIdentifier": "94361", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Saito, Kuniaki"}], "nameIdentifiers": [{"nameIdentifier": "94362", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurita, Kenichi"}], "nameIdentifiers": [{"nameIdentifier": "94363", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ozaki, Norio"}], "nameIdentifiers": [{"nameIdentifier": "94364", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-07-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "20190315_draft revised.pdf", "filesize": [{"value": "304.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 304400.0, "url": {"label": "20190315_draft revised", "url": "https://nagoya.repo.nii.ac.jp/record/28729/files/20190315_draft revised.pdf"}, "version_id": "8d469dbc-25d3-47c1-9f50-5d78f45135cd"}, {"accessrole": "open_date", "date": [{"dateType": 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patients with somatic symptom disorder with predominant pain around the orofacial region"], "weko_shared_id": null}