{"_buckets": {"deposit": "06f2adc2-9ff4-47d6-bab7-18c6e9095533"}, "_deposit": {"id": "28729", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28729"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028729", "sets": ["501"]}, "author_link": ["94353", "94354", "94355", "94356", "94357", "94358", "94359", "94360", "94361", "94362", "94363", "94364"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageStart": "e2698", "bibliographicVolumeNumber": "34", "bibliographic_titles": [{"bibliographic_title": "Human Psychopharmacology: Clinical and Experimental", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Objective: Burning mouth syndrome (BMS) and atypical odontalgia (AO) are examples of somatic symptom disorders with predominant pain around the orofacial region. Neuroinflammation is thought to play a role in the mechanisms, but few studies have been conducted. We aimed to better understand the role of neuroinflammation in the pathophysiology and treatment of BMS/AO. Methods: Plasma levels of 28 neuroinflammation‐related molecules were determined in 44 controls and 48 BMS/AO patients both pretreatment and 12‐week post‐treatment with duloxetine. Results: Baseline plasma levels of interleukin (IL)‐1β (p \u003c .0001), IL‐1 receptor antagonist (p \u003c .001), IL‐6 (p \u003c .0001), macrophage inflammatory protein‐1β (p \u003c .0001), and platelet‐derived growth factor‐bb (.04) were significantly higher in patients than in controls. Plasma levels of granulocyte macrophage colony stimulating factor were significantly higher in patients than in controls (p \u003c .001) and decreased with treatment (.009). Plasma levels of eotaxin, monocyte chemoattractant protein‐1, and vascular endothelial growth factor decreased significantly with treatment (p \u003c .001, .022, and .029, respectively). Conclusions: Inflammatory mechanisms may be involved in the pathophysiology and/or treatment response of somatic symptom disorders with predominant pain around the orofacial region.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "ファイル公開：2020-07-01", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Wiley", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1002/hup.2698", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This is the peer reviewed version of the following article: [ Miyauchi, T, Tokura, T, Kimura, H, et al. Effect of antidepressant treatment on plasma levels of neuroinflammation‐associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region. Hum Psychopharmacol Clin Exp. 2019; 34:e2698. https://doi.org/10.1002/hup.2698], which has been published in final form at [https://doi.org/10.1002/hup.2698]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN（print）", "attribute_value_mlt": [{"subitem_source_identifier": "0885-6222", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Miyauchi, Tomoya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "94353", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tokura, Tatsuya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "94354", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kimura, Hiroyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "94355", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Mikiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "94356", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umemura, Eri", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "94357", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato (Boku), Aiji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "94358", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagashima, Wataru", "creatorNameLang": "en"}], 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odontalgia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "burning mouth syndrome", "subitem_subject_scheme": "Other"}, {"subitem_subject": "chemokines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cytokines", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neuroinflammation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "somatic symptom disorder with predominant pain", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Effect of antidepressant treatment on plasma levels of neuroinflammation‐associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": 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