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  1. B200 工学部/工学研究科
  2. B200a 雑誌掲載論文
  3. 学術雑誌

Loop extrusion drives very different dynamics for Rouse chains in bulk solutions and at interfaces

http://hdl.handle.net/2237/00031022
http://hdl.handle.net/2237/00031022
4bfbd707-c833-458b-963d-99acf6cacd69
名前 / ファイル ライセンス アクション
TYTSHSEPL20190301revVer2.pdf TYTSHSEPL20190301revVer2 (185.0 kB)
TYTSHSEPL20190301revVer2Suppl.pdf TYTSHSEPL20190301revVer2Suppl (68.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-12-19
タイトル
タイトル Loop extrusion drives very different dynamics for Rouse chains in bulk solutions and at interfaces
言語 en
著者 Yamamoto, Tetsuya

× Yamamoto, Tetsuya

WEKO 94891

en Yamamoto, Tetsuya

Search repository
Sakaue, Takahiro

× Sakaue, Takahiro

WEKO 94892

en Sakaue, Takahiro

Search repository
Schiessel, Helmut

× Schiessel, Helmut

WEKO 94893

en Schiessel, Helmut

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 This is an author-created, un-copyedited version of an article published in {EPL (Europhysics Letters)}. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at {https://doi.org/10.1209/0295-5075/127/38002}.
抄録
内容記述 The loop extrusion theory predicts that the loops of chromosomes are produced by cohesin molecules that uni-directionally extrude a chromatin fiber. We here use an extension of the Rouse model to predict the chain conformational dynamics driven by the loop extrusion process. Our theory predicts that in a bulk solution, the mean square distance between the starting and ending sites of the loop extrusion process decreases with a constant rate. This is because the tension generated by the loop extrusion process drives the displacement of the starting site towards the ending site. In contrast, when the cohesin is entrapped at an interface, the mean square distance does not decrease until the tension generated by the loop extrusion process arrives at the ending site. This theory highlights the fact that the chain dynamics strongly depends on the mobility of the chain segments bound by cohesin.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2020-09-05
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 IOP publishing
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1209/0295-5075/127/38002
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 1286-4854
書誌情報 en : EPL (Europhysics Letters)

巻 127, 号 3, p. 38002, 発行日 2019-09-05
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