{"_buckets": {"deposit": "3ec03881-bd3c-4ada-9d40-3b895e97b743"}, "_deposit": {"id": "28837", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28837"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028837"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "513", "bibliographicPageStart": "507", "bibliographicVolumeNumber": "22", "bibliographic_titles": [{"bibliographic_title": "Pituitary"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Purpose: Functional pituitary adenomas (FPAs) lacking a well-defined pseudocapsule can invade the adjacent pituitary gland. In such situations, peel-off resection of the adjacent pituitary gland after selective adenomectomy might lead to complete tumor removal, resulting in optimal endocrinological outcomes. Here, we present the significance of peel-off resection of the pituitary gland in patients with FPA in whom complete extracapsular tumor removal cannot be achieved. Methods: We performed a retrospective review of 21 patients with FPA who underwent transsphenoidal surgery (TSS). After selective adenomectomy, peel-off resection of the adjacent pituitary gland was performed in 13 patients because complete extracapsular resection could not be achieved, while peel-off resection was not performed in the remaining 8 patients because complete extracapsular resection was accomplished. The clinical outcomes of these groups were compared. The pituitary tissues obtained by peel-off resection were pathologically examined for tumor cells. Results: Early postoperative biochemical remission was achieved in 20 patients (95.2%). Anterior pituitary functions were not aggravated postoperatively in any patient: however, transient diabetes insipidus (DI) occurred in 2 patients. There were no statistically significant differences in the clinical outcomes of the two groups. A pseudocapsule was pathologically detected in the adjacent anterior pituitary even in patients in whom no pseudocapsule was intraoperatively detected. Tumor cells were pathologically detected in 7 (58.3%) of 12 pituitary tissues examined. Conclusions: Peel-off resection of the pituitary gland, which can remove a small tumor cell remnant in the adjacent pituitary, might maximize the effectiveness of TSS with minimal impact on postoperative pituitary function.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2020/10/01", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Springer"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1007/s11102-019-00980-w", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\u201cThis is a post-peer-review, pre-copyedit version of an article published in [Pituitary]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11102-019-00980-w\u201d."}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "1386-341X", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nagata, Yuichi"}], "nameIdentifiers": [{"nameIdentifier": "94903", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takeuchi, Kazuhito"}], "nameIdentifiers": [{"nameIdentifier": "94904", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Taiki"}], "nameIdentifiers": [{"nameIdentifier": "94905", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishikawa, Takayuki"}], "nameIdentifiers": [{"nameIdentifier": "94906", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawabata, Teppei"}], "nameIdentifiers": [{"nameIdentifier": "94907", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimoyama, Yoshie"}], "nameIdentifiers": [{"nameIdentifier": "94908", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Inoshita, Naoko"}], "nameIdentifiers": [{"nameIdentifier": "94909", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Wakabayashi, Toshihiko"}], "nameIdentifiers": [{"nameIdentifier": "94910", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-10-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Manuscript.pdf", "filesize": [{"value": "194.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 194100.0, "url": {"label": "Manuscript", "url": "https://nagoya.repo.nii.ac.jp/record/28837/files/Manuscript.pdf"}, "version_id": "aa0ffc9e-1c7e-49f5-989d-646793fdb0ff"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Pituitary resection", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Transsphenoidal surgery", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pseudocapsule", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Pituitary adenoma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Acromegaly", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cushing disease", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function"}]}, "item_type_id": "10", "owner": "1", "path": ["499/500/501"], "permalink_uri": "http://hdl.handle.net/2237/00031024", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2019-12-20"}, "publish_date": "2019-12-20", "publish_status": "0", "recid": "28837", "relation": {}, "relation_version_is_last": true, "title": ["Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function"], "weko_shared_id": null}