{"_buckets": {"deposit": "82c6a3dd-2781-4185-82fa-17443438ec48"}, "_deposit": {"id": "30091", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "30091"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00030091"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "289", "bibliographicPageStart": "281", "bibliographicVolumeNumber": "82", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "It is unsettled whether increased exercise ventilation in Fontan subjects is due to increased pulmonary dead space or augmented ventilatory drive. Twenty-six Fontan patients underwent symptom-limited treadmill cardiopulmonary exercise testing. Two groups of age- and sex- matched subjects served as controls: the biventricularly repaired (Bi, n = 18), and the \u201ctrue\u201d control (C, n = 29) groups. Peak oxygen uptake (VO2peak) was not different among groups (41.0 +/\u2013 8.4 ml/min/kg, 43.5 +/\u2013 6.6 ml/min/kg, and 45.9 +/\u2013 11.6 ml/min/kg for Fontan, Bi, and C groups, respectively, p = 0.16). Fontan subjects, however, showed steeper alveolar ventilation/carbon-dioxide (VA/VCO2) regression slope (35.5 +/\u2013 5.3, 28.7 +/\u2013 3.8, and 29.5 +/\u2013 3.0 l/ml, for Fontan, Bi, and C groups, respectively, p\u003c0.0001), and lower end-expiratory carbon-dioxide fraction (FetCO2VAT) at ventilatory threshold (VAT) (4.4 +/\u2013 0.5%, 5.5 +/\u2013 0.5%, and 5.5 +/\u2013 0.4%, for Fontan, Bi, and C groups, respectively, p\u003c0.001). The dead-space ventilation fraction at VAT was similar among groups (0.33 +/\u2013 0.06, 0.33 +/\u2013 0.04, 0.35 +/\u2013 0.05 for Fontan, Bi, and C groups, respectively, p = 0.54). In Fontan subjects, arterial oxygen saturation at rest (SaO2rest) was correlated with VA/VCO2 regression slope (r = \u20130.41, p = 0.04) and with FetCO2VAT (p = \u20130.53, p\u003c0.01). We conclude that Fontan patients show exercise hyperventilation due to augmented central and/or peripheral ventilatory drive, which is further augmented by residual hypoxemia.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.82.2.281", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University Graduate School of Medicine, School of Medicine"}]}, "item_9_relation_43": {"attribute_name": "\u7570\u7248\u3067\u3042\u308b", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/822.html ", "subitem_relation_type_select": "URI"}}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_61": {"attribute_name": "ISSN\uff08Online\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "2186-3326", "subitem_source_identifier_type": "ISSN"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Okamura, Yukiko"}], "nameIdentifiers": [{"nameIdentifier": "99312", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kito, Machiko"}], "nameIdentifiers": [{"nameIdentifier": "99313", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yasuda, Kazushi"}], "nameIdentifiers": [{"nameIdentifier": "99314", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Baba, Reizo"}], "nameIdentifiers": [{"nameIdentifier": "99315", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-06-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "12_Okamura.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "12_Okamura.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/30091/files/12_Okamura.pdf"}, "version_id": "82c99fc5-56bd-4703-b40d-ae87ea6cdc0b"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Fontan", "subitem_subject_scheme": "Other"}, {"subitem_subject": "exercise tolerance", "subitem_subject_scheme": "Other"}, {"subitem_subject": "oxygen uptake efficiency slope", "subitem_subject_scheme": "Other"}, {"subitem_subject": "maximal oxygen uptake", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ventilatory response", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Contributions of residual hypoxemia to exercise hyperventilation in Fontan patients", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Contributions of residual hypoxemia to exercise hyperventilation in Fontan patients"}]}, "item_type_id": "9", "owner": "1", "path": ["499/508/509/2504"], "permalink_uri": "https://doi.org/10.18999/nagjms.82.2.281", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2020-06-01"}, "publish_date": "2020-06-01", "publish_status": "0", "recid": "30091", "relation": {}, "relation_version_is_last": true, "title": ["Contributions of residual hypoxemia to exercise hyperventilation in Fontan patients"], "weko_shared_id": null}