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Impact of age on clinicopathological features and survival of epithelial ovarian neoplasms in reproductive age
http://hdl.handle.net/2237/00032352
http://hdl.handle.net/2237/00032352b41a8d71-ca95-4e33-92b2-e08a144c2304
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AuthorManuscript (433.0 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-06-12 | |||||
| タイトル | ||||||
| タイトル | Impact of age on clinicopathological features and survival of epithelial ovarian neoplasms in reproductive age | |||||
| 言語 | en | |||||
| 著者 |
Hanatani, Maya
× Hanatani, Maya× Yoshikawa, Nobuhisa× Yoshida, Kosuke× Tamauchi, Satoshi× Ikeda, Yoshiki× Nishino, Kimihiro× Niimi, Kaoru× Suzuki, Shiro× Kawai, Michiyasu× Kajiyama, Hiroaki× Kikkawa, Fumitaka |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | “This is a post-peer-review, pre-copyedit version of an article published in [International Journal of Clinical Oncology]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10147-019-01550-7”. | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Ovarian neoplasm | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Epithelial ovarian cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Fertility preservations | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Age group | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Survival | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Little is known about the effect of age on the prognosis of epithelial ovarian neoplasms. In the reproductive age, fertility-sparing surgery had been widely implemented. This study aimed to elucidate impact of age on the clinicopathologic characteristics and survival of epithelial ovarian neoplasms in the reproductive age. Methods: The clinical records of patients diagnosed as epithelial ovarian cancer or epithelial borderline ovarian tumor at the age of 40 years or younger at multiple institutions in the Tokai Ovarian Tumor Study Group were reviewed retrospectively. All patients were stratified into two age groups: group A (≤ 30 years) and group B (31–40 years). Univariate and multivariate analyses were performed to evaluate overall survival and disease-free survival. Results: A total of 583 patients (325 patients: cancer, 258 patients: borderline) were included. The median follow-up time was 62.0 months (range 1–270 months). Compared with group B, group A had a significantly higher rate of borderline tumor (66.7% vs. 32.7%, p < 0.001); stage I disease (85.9% vs. 70.4%, p < 0.001); mucinous type (69.2% vs. 35.6%, p < 0.001); conservative surgery (83.8% vs. 41.6%, p < 0.001); no adjuvant chemotherapy (67.2% vs. 44.7%, p < 0.001); and CA125 ≤ 35 U/mL (39.4% vs. 28.8%, p < 0.05). There was a significant difference in the overall survival (p = 0.0051) and the disease-free survival (p = 0.0039) between the two groups. Multivariate analysis revealed that the independent prognostic factors for the overall survival were age, stage, histology, and ascitic fluid cytology. Conclusion: In epithelial ovarian neoplasms, younger patients had a survival advantage over older patients. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ファイル公開：2021/01/01 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | Springer | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1007/s10147-019-01550-7 | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1341-9625 | |||||
| 書誌情報 |
en : International Journal of Clinical Oncology 巻 25, 号 1, p. 187-194, 発行日 2020-01 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
