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Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer
http://hdl.handle.net/2237/00032354
http://hdl.handle.net/2237/00032354e87f6c1f-574f-4c40-8a99-a5bbd431e565
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-06-12 | |||||
タイトル | ||||||
タイトル | Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer | |||||
言語 | en | |||||
著者 |
Nakagawa, Nobuhiko
× Nakagawa, Nobuhiko× Yamada, Suguru× Sonohara, Fuminori× Takami, Hideki× Hayashi, Masamichi× Kanda, Mitsuro× Kobayashi, Daisuke× Tanaka, Chie× Nakayama, Goro× Koike, Masahiko× Fujiwara, Michitaka× Kodera, Yasuhiro |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | “This is a post-peer-review, pre-copyedit version of an article published in [Annals of Surgical Oncology]. The final authenticated version is available online at: http://dx.doi.org/10.1245/s10434-019-08047-7”. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Nutritional and immunological statuses are attracting increasing attention for their ability to predict surgical outcomes in various cancers. The Naples prognostic score (NPS) consists of the serum albumin level, total cholesterol level, neutrophil-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio and could be useful for predicting survival. Patients and Methods: We retrospectively analyzed 196 patients with pancreatic cancer who underwent curative R0/R1 resection with a surgery-first strategy between June 2003 and August 2016. The NPS of the patients was calculated from preoperative data, and the patients were then divided into three groups based on their NPS. Clinicopathological characteristics, surgical outcomes, and long-term survival were compared, and multivariate analysis of overall survival was conducted. Results: Of a total of 196 patients, 22 were classified into group 0 (NPS 0), 113 into group 1 (NPS 1 or 2), and 61 into group 2 (NPS 3 or 4). Median survival time was 103.4 months in group 0, 33.3 months in group 1, and 21.3 months in group 2. Significant survival differences were observed among the 3 groups (group 1 vs. 2, group 0 vs. 2, P = 0.0380, P = 0.0022, respectively). On multivariate analysis, NPS was identified as an independent prognostic factor [hazard ratio (HR) = 1.78; P = 0.0131]; however, there were no significant differences in the incidence of postoperative morbidity among the NPS groups. Conclusions: The NPS could be an easy scoring system and an independent preoperative predictor of survival. | |||||
言語 | en | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | ファイル公開:2021/03/01 | |||||
言語 | ja | |||||
出版者 | ||||||
出版者 | Springer | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1245/s10434-019-08047-7 | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1068-9265 | |||||
書誌情報 |
en : Annals of Surgical Oncology 巻 27, 号 3, p. 887-895, 発行日 2020-03 |
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著者版フラグ | ||||||
値 | author |