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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 66(3-4)

Transgenic rat models of vasopressin overexpression

https://doi.org/10.18999/nagjms.66.3-4.87
https://doi.org/10.18999/nagjms.66.3-4.87
1ece55f3-f3fe-4460-b98e-16eaad88508a
名前 / ファイル ライセンス アクション
nj6632.pdf nj6632.pdf (50.4 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2006-02-10
タイトル
タイトル Transgenic rat models of vasopressin overexpression
著者 Oiso, Yutaka

× Oiso, Yutaka

WEKO 10131

Oiso, Yutaka

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Nagasaki, Hiroshi

× Nagasaki, Hiroshi

WEKO 10132

Nagasaki, Hiroshi

Search repository
Yokoi, Hisashi

× Yokoi, Hisashi

WEKO 10133

Yokoi, Hisashi

Search repository
キーワード
主題Scheme Other
主題 vasopressin
キーワード
主題Scheme Other
主題 V2 receptor
キーワード
主題Scheme Other
主題 transgenic rat
キーワード
主題Scheme Other
主題 downregulation
抄録
内容記述 Vasopressin has an important role in water metabolism and its impairment induces some clinical disorders such as diabetes insipidus or syndrome of inappropriate antidiuresis (SIAD). SIAD is caused by the overproduction of vasopressin which induces diluting hyponatremia. The accurate diagnosis and appropriate therapy have not settled up to date because its pathophysiology is very complicated. It is meaningful to develop a rat model of SIAD in which human vasopressin gene is overexpressed in order to analyze pathophysiological changes. Several models transgenic for vasopressin including us had been generated. The transgenic rats provide a useful model to investigate various pathophysiological changes resulting from the oversecretion of vasopressin. Some interesting results based on these animal models are reviewed.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.66.3-4.87
ID登録タイプ JaLC
書誌情報 Nagoya Journal of Medical Science

巻 66, 号 3-4, p. 87-93, 発行日 2003-11
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/5393
識別子タイプ HDL
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