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Transgenic rat models of vasopressin overexpression
https://doi.org/10.18999/nagjms.66.3-4.87
https://doi.org/10.18999/nagjms.66.3-4.871ece55f3-f3fe-4460-b98e-16eaad88508a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
nj6632.pdf (50.4 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-02-10 | |||||
| タイトル | ||||||
| タイトル | Transgenic rat models of vasopressin overexpression | |||||
| 言語 | en | |||||
| 著者 |
Oiso, Yutaka
× Oiso, Yutaka× Nagasaki, Hiroshi× Yokoi, Hisashi |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | vasopressin | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | V2 receptor | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | transgenic rat | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | downregulation | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Vasopressin has an important role in water metabolism and its impairment induces some clinical disorders such as diabetes insipidus or syndrome of inappropriate antidiuresis (SIAD). SIAD is caused by the overproduction of vasopressin which induces diluting hyponatremia. The accurate diagnosis and appropriate therapy have not settled up to date because its pathophysiology is very complicated. It is meaningful to develop a rat model of SIAD in which human vasopressin gene is overexpressed in order to analyze pathophysiological changes. Several models transgenic for vasopressin including us had been generated. The transgenic rats provide a useful model to investigate various pathophysiological changes resulting from the oversecretion of vasopressin. Some interesting results based on these animal models are reviewed. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.66.3-4.87 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 66, 号 3-4, p. 87-93, 発行日 2003-11 |
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| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/5393 | |||||
| 識別子タイプ | HDL | |||||
