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  1. F100 環境医学研究所
  2. F100b 紀要
  3. Environmental medicine : annual report of the Research Institute of Environmental Medicine
  4. 47

Effect of ACTH on the Proliferation of the Rat Adrenal Gland

https://doi.org/10.18999/envm.47.20
https://doi.org/10.18999/envm.47.20
183dcb9d-e2a5-4f30-a30f-f48a8c9e32e4
名前 / ファイル ライセンス アクション
20-21.pdf 20-21.pdf (230.1 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-04-05
タイトル
タイトル Effect of ACTH on the Proliferation of the Rat Adrenal Gland
言語 en
著者 Kobayashi, Hironobu

× Kobayashi, Hironobu

WEKO 15826

en Kobayashi, Hironobu

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Imai, Tsuneo

× Imai, Tsuneo

WEKO 15827

en Imai, Tsuneo

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Kambe, Fukushi

× Kambe, Fukushi

WEKO 15828

en Kambe, Fukushi

Search repository
Mirza, Rusella

× Mirza, Rusella

WEKO 15829

en Mirza, Rusella

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Seo, Hisao

× Seo, Hisao

WEKO 15830

en Seo, Hisao

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 ACTH
キーワード
主題Scheme Other
主題 PCNA
キーワード
主題Scheme Other
主題 adrenal gland
キーワード
主題Scheme Other
主題 proliferation
抄録
内容記述 Although the regulation of steroidogenesis in adrenal fasciculate and reticularis is stimulated by adrenocorticotrophic hormone (ACTH), its role on the proliferation of adrenocortical call is not established. We thus investigated the effect of ACTH on the proliferation of adrenocortical cells by analyzing the expression of proliferating cell nuclear antigen (PCNA). Endogeneous secretion of ACTH was inhibited by treatment with dexamethasone for 5 days. At intervals after ACTH treatment, homogenate of the adrenal gland was subjected to Western blot analysis. PCNA expression was detected in control rat without any treatment. Dexamethasone administration for 5 days resulted in the reduction of PCNA expression. ACTH administration to the dexamethasone treated rats increased PCNA expression at 24 hr. It is thus demonstrated that ACTH increases cellular proliferation in adrenal cortex.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 国立情報学研究所で電子化したコンテンツを使用している。
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Reaserch Institue of Environmental Medicine, Nagoya University
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/envm.47.20
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 0287-0517
書誌情報 en : Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University

巻 47, p. 20-21, 発行日 2003-12
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/7562
識別子タイプ HDL
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