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Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction
https://doi.org/10.18999/envm.47.37
https://doi.org/10.18999/envm.47.37fc260d23-c7e0-4775-9581-d08215aa8d93
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
37-38.pdf (209.5 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-04-05 | |||||
| タイトル | ||||||
| タイトル | Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction | |||||
| 言語 | en | |||||
| 著者 |
Takemura, Haruki
× Takemura, Haruki× Yasui, Kenji× Niwa, Noriko× Hojo, Mayumi× Horiba, Mitsuru× Lee, Jong-Kook× Yuichi, Ueda× Kodama, Itsuo |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | gap junction | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | connexin43 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | mouse | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hypertrophy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | myocardial infarction | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Gap junction remodeling have been reported in various types of heart disease. Information available for the gap junction remodeling after myocardial infarction is still limited. In the present study, we investigated mRNA expression of connexin 43 (Cx43), major protein of gap junction channels in compensated hypertrophied interventricular septum (IVS) after myocardial infarction (MI) in mice by using a real time quantitative PCR expression. Cx43 mRNA expression in the interventricular septum of MI mouse was significantly decreased by 2 fold (813.7±252.6 molecules / 10^5 GAPDH molecules) compared to non-operated control (1628.9±180.9) and sham-operated mice (2051.9±169.8). There was no significant difference in Cx43 mRNA between control and sham groups. Down-regulation of Cx43 mRNA in compensated hypertrophied myocardium could be involved in the arrythmogenic substrate in the heart after MI. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 国立情報学研究所で電子化したコンテンツを使用している。 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | Research Institute of Environmental Medicine, Nagoya University | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/envm.47.37 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0287-0517 | |||||
| 書誌情報 |
en : Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University 巻 47, p. 37-38, 発行日 2003-12 |
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| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/7571 | |||||
| 識別子タイプ | HDL | |||||
