{"_buckets": {"deposit": "f6e81f80-3b3f-4e86-9cf9-49659b9052a1"}, "_deposit": {"id": "5958", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "5958"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00005958"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2003-12", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "38", "bibliographicPageStart": "37", "bibliographicVolumeNumber": "47", "bibliographic_titles": [{"bibliographic_title": "Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Gap junction remodeling have been reported in various types of heart disease. Information available for the gap junction remodeling after myocardial infarction is still limited. In the present study, we investigated mRNA expression of connexin 43 (Cx43), major protein of gap junction channels in compensated hypertrophied interventricular septum (IVS) after myocardial infarction (MI) in mice by using a real time quantitative PCR expression. Cx43 mRNA expression in the interventricular septum of MI mouse was significantly decreased by 2 fold (813.7\u00b1252.6 molecules / 10^5 GAPDH molecules) compared to non-operated control (1628.9\u00b1180.9) and sham-operated mice (2051.9\u00b1169.8). There was no significant difference in Cx43 mRNA between control and sham groups. Down-regulation of Cx43 mRNA in compensated hypertrophied myocardium could be involved in the arrythmogenic substrate in the heart after MI.", "subitem_description_type": "Abstract"}]}, "item_9_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u56fd\u7acb\u60c5\u5831\u5b66\u7814\u7a76\u6240\u3067\u96fb\u5b50\u5316\u3057\u305f\u30b3\u30f3\u30c6\u30f3\u30c4\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3002", "subitem_description_type": "Other"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/7571"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/envm.47.37", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Research Institute of Environmental Medicine, Nagoya University"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0287-0517", "subitem_source_identifier_type": "ISSN"}]}, "item_9_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Takemura, Haruki"}], "nameIdentifiers": [{"nameIdentifier": "15858", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yasui, Kenji"}], "nameIdentifiers": [{"nameIdentifier": "15859", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Niwa, Noriko"}], "nameIdentifiers": [{"nameIdentifier": "15860", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hojo, Mayumi"}], "nameIdentifiers": [{"nameIdentifier": "15861", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Horiba, Mitsuru"}], "nameIdentifiers": [{"nameIdentifier": "15862", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Lee, Jong-Kook"}], "nameIdentifiers": [{"nameIdentifier": "15863", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yuichi, Ueda"}], "nameIdentifiers": [{"nameIdentifier": "15864", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kodama, Itsuo"}], "nameIdentifiers": [{"nameIdentifier": "15865", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "37-38.pdf", "filesize": [{"value": "209.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 209500.0, "url": {"label": "37-38.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/5958/files/37-38.pdf"}, "version_id": "40859036-c57d-4940-8917-e36a5e0f1746"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "gap junction", "subitem_subject_scheme": "Other"}, {"subitem_subject": "connexin43", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mouse", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hypertrophy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "myocardial infarction", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction"}]}, "item_type_id": "9", "owner": "1", "path": ["329/333/334/737"], "permalink_uri": "https://doi.org/10.18999/envm.47.37", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2007-04-05"}, "publish_date": "2007-04-05", "publish_status": "0", "recid": "5958", "relation": {}, "relation_version_is_last": true, "title": ["Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction"], "weko_shared_id": null}