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  1. F100 環境医学研究所
  2. F100b 紀要
  3. Environmental medicine : annual report of the Research Institute of Environmental Medicine
  4. 46(1-2)

Estrogen Enhances Vitamin D_3-mediated Expression of Osteocalcin mRNA by Increasing Vitamin D_3 Receptor Expression in Osteoblasts

https://doi.org/10.18999/envm.46.43
https://doi.org/10.18999/envm.46.43
54c53181-15e9-43f4-93be-650f509f7643
名前 / ファイル ライセンス アクション
KJ00000034859.pdf KJ00000034859.pdf (210.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2006-01-05
タイトル
タイトル Estrogen Enhances Vitamin D_3-mediated Expression of Osteocalcin mRNA by Increasing Vitamin D_3 Receptor Expression in Osteoblasts
言語 en
著者 KAWANO, Setsuko

× KAWANO, Setsuko

WEKO 3106

en KAWANO, Setsuko

Search repository
KAMBE, Fukushi

× KAMBE, Fukushi

WEKO 3107

en KAMBE, Fukushi

Search repository
KANDA, Kazumi

× KANDA, Kazumi

WEKO 3108

en KANDA, Kazumi

Search repository
OHMORI, Sachiko

× OHMORI, Sachiko

WEKO 3109

en OHMORI, Sachiko

Search repository
SEO, Hisao

× SEO, Hisao

WEKO 3110

en SEO, Hisao

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 estrogen
キーワード
主題Scheme Other
主題 1α,25-dihydroxyvitamin D_3
キーワード
主題Scheme Other
主題 osteocalcin
キーワード
主題Scheme Other
主題 1α,25-dihydroxyvitamin D_3 receptor
抄録
内容記述 Regulation of osteocalcin (OC) gene expression in osteoblasts by estrogen has been controversial. We thus investigated the effect of 17β-estradiol (Ea) on 1α,25-dihydroxyvitamin D_3 (VD_3)-mediated increase in the transcription of OC gene in rat osteoblastic ROS 17/2.8 cells. Treatment of the cells with E_2 or VD_3 alone did not increase OC mRNA. However, combined treatment with E_2 and VD_3 significantly increased the OC mRNA levels, suggesting that VD_3-dependent up-regulation of OC expression requires E_2 action. Since it was demonstrated that treatment with E_2 alone increased the expression of VD_3 receptor mRNA, it was suggested that E_2- mediated increase in the receptor number is contributing to VD_3-mediated increase in OC gene transcription.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 国立情報学研究所で電子化したコンテンツを使用している。
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Research Institute of Environmental Medicine, Nagoya University
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/envm.46.43
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 02870517
書誌情報 en : Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University

巻 46, 号 1/2, p. 43-44, 発行日 2002-12
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/2779
識別子タイプ HDL
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