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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 32(3-4)

Clinical and Biochemical Study of Accidents in Peridurography

https://doi.org/10.18999/nagjms.32.3-4.429
https://doi.org/10.18999/nagjms.32.3-4.429
5994ed4a-e70b-4fe4-9220-53702b1e673d
名前 / ファイル ライセンス アクション
v32n34p429_444.pdf v32n34p429_444.pdf (2.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-10-04
タイトル
タイトル Clinical and Biochemical Study of Accidents in Peridurography
著者 NAGAMINE, KOICHI

× NAGAMINE, KOICHI

WEKO 98583

NAGAMINE, KOICHI

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抄録
内容記述 Since the experiences of severe side effects of peridurographic examination have been reported, this procedure has been used less frequently in spite of its easy to get. The most remarkable symptoms of accidents were clonic convnlsion, disturbances of speech and consciousness, headache, hyperperspiration and myalgia. Physical examinations revealed always increase of tendon reflex and sometimes pathologic reflex. The accidents could be caused by intraspinal administration of water-soluble contrast medium (Diatrizoate), and also there is a report that there was an accident only when contrast medium was injected in the cranial portion of the subarachnoid space. Contrast medium permeates through the dura mater. Its permeability rate was about 0.4% in the patient with normal meninges. Since some agents which affect carbohydrate metabolism was found to cause acute convulsion, and decrease of ATP production or ATP utilization was considered to have close relation to consciousness, the effects of the contrast medium on hexokinase activity and mitochondrial respiration of rat brain were examined, and noticeable inhibitory effects were found. The inhibitory effect on D-amino acid oxidase was also observed. The medium had no effects on the succinic dehydrogenase activity, but it had remarkable effects on the state 3 respiration, and decrease of P:0 ratio indicated decrease of ATP production. These results suggest that the watersoluble contrast medium, which is injected in the subarachnoid space, stimulates the cerebral cortex and produces the metabolic disturbances of the brain which might have some relation to development of the accidents.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.32.3-4.429
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 32, 号 3-4, p. 429-444, 発行日 1970-03
著者版フラグ
値 publisher
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