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A femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica
http://hdl.handle.net/2237/00030159
65f48f44-87e6-456c-8a2f-9a836f3b5c01
名前 / ファイル | ライセンス | アクション | |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-05-10 | |||||
タイトル | ||||||
タイトル | A femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica | |||||
著者 |
Uraguchi, Daisuke
× Uraguchi, Daisuke× Kuwata, Keiko× Hijikata, Yuh× Yamaguchi, Rie× Imaizumi, Hanae× AM, Sathiyanarayanan× Rakers, Christin× Mori, Narumi× Akiyama, Kohki× Irle, Stephan× McCourt, Peter× Kinoshita, Toshinori× Ooi, Takashi× Tsuchiya, Yuichiro |
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権利 | ||||||
権利情報 | “This is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in [Science] on [v.362, n.6420, 14 Dec 2018], DOI: [10.1126/science.aau5445].” | |||||
抄録 | ||||||
内容記述 | The parasitic plant Striga hermonthica has been causing devastating damage to the crop production in Africa. Because Striga requires host-generated strigolactones to germinate, the identification of selective and potent strigolactone agonists could help control these noxious weeds. We developed a selective agonist, sphynolactone-7, a hybrid molecule originated from chemical screening, that contains two functional modules derived from a synthetic scaffold and a core component of strigolactones. Cooperative action of these modules in the activation of a high-affinity strigolactone receptor ShHTL7 allows sphynolactone-7 to provoke Striga germination with potency in the femtomolar range. We demonstrate that sphynolactone-7 is effective for reducing Striga parasitism without impinging on host strigolactone-related processes. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | American Association for the Advancement of Science | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
DOI | ||||||
関連識別子 | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1126/science.aau5445 | |||||
ISSN(print) | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0036-8075 | |||||
書誌情報 |
Science 巻 362, 号 6420, p. 1301-1305, 発行日 2018-12-14 |
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著者版フラグ | ||||||
値 | author |