{"_buckets": {"deposit": "25ae43b3-b64e-481b-b153-399dbf0f3403"}, "_deposit": {"id": "9539", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "9539"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00009539"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1-2", "bibliographicPageEnd": "18", "bibliographicPageStart": "11", "bibliographicVolumeNumber": "71", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A mouse jejunum, when incubated in vitro in Ussing chambers, was found to exhibit morphological deterioration of the villi with denudation of the epithelia (J Nutr Sci Vitaminol, 51: 406, 2005). Our study examined the involvement of apoptosis in an intestinal injury model by a DNA ladder assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay. Electrophoresis of mucosal DNA revealed ladders, indicating the occurrence of DNA fragmentation. Cells with TUNEL-positive nuclei were detected among the villus epithelial cells (enterocytes), whereas they are rarely seen among crypt epithelial cells. These features were evident within 1 h after the start of incubation. Apoptotic death of the enterocytes was thus involved in the destruction of villi when incubated in Ussing chambers.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/11332"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.71.1-2.11", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University School of Medicine"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "ISSN"}]}, "item_9_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "INAGAKI-TACHIBANA, EIKO"}], "nameIdentifiers": [{"nameIdentifier": "27534", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TSUKAHARA, TAKAMITSU"}], "nameIdentifiers": [{"nameIdentifier": "27535", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KAJI, KAZUHIKO"}], "nameIdentifiers": [{"nameIdentifier": "27536", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "EGUCHI, RYOJI"}], "nameIdentifiers": [{"nameIdentifier": "27537", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KANAZAWA, HIROAKI"}], "nameIdentifiers": [{"nameIdentifier": "27538", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "HAYASHI, HISAYOSHI"}], "nameIdentifiers": [{"nameIdentifier": "27539", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "SUZUKI, YUICHI"}], "nameIdentifiers": [{"nameIdentifier": "27540", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "p011-018_Tachibana.pdf", "filesize": [{"value": "611.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 611400.0, "url": {"label": "p011-018_Tachibana.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/9539/files/p011-018_Tachibana.pdf"}, "version_id": "32785a69-6020-40e4-8cb6-730cca8f15d4"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Apoptosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "DNA ladder", "subitem_subject_scheme": "Other"}, {"subitem_subject": "TUNEL staining", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Villus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Intestinal barrier", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "INVOLVEMENT OF DNA FRAGMENTATION OF ENTEROCYTES IN MUCOSAL INJURY TO A MOUSE JEJUNUM INCUBATED IN USSING CHAMBERS", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "INVOLVEMENT OF DNA FRAGMENTATION OF ENTEROCYTES IN MUCOSAL INJURY TO A MOUSE JEJUNUM INCUBATED IN USSING CHAMBERS"}]}, "item_type_id": "9", "owner": "1", "path": ["499/508/509/1110"], "permalink_uri": "https://doi.org/10.18999/nagjms.71.1-2.11", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2009-03-16"}, "publish_date": "2009-03-16", "publish_status": "0", "recid": "9539", "relation": {}, "relation_version_is_last": true, "title": ["INVOLVEMENT OF DNA FRAGMENTATION OF ENTEROCYTES IN MUCOSAL INJURY TO A MOUSE JEJUNUM INCUBATED IN USSING CHAMBERS"], "weko_shared_id": 3}